ID G3HSH5_CRIGR Unreviewed; 868 AA.
AC G3HSH5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Centrosomal protein 97 {ECO:0000313|Ensembl:ENSCGRP00001014716.1};
DE SubName: Full=Centrosomal protein of 97 kDa {ECO:0000313|EMBL:EGW00799.1};
GN Name=Cep97 {ECO:0000313|Ensembl:ENSCGRP00001014716.1};
GN ORFNames=I79_013807 {ECO:0000313|EMBL:EGW00799.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW00799.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW00799.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001014716.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; JH000664; EGW00799.1; -; Genomic_DNA.
DR RefSeq; XP_003506477.1; XM_003506429.3.
DR STRING; 10029.G3HSH5; -.
DR PaxDb; 10029-XP_007632316-1; -.
DR Ensembl; ENSCGRT00001018954.1; ENSCGRP00001014716.1; ENSCGRG00001015516.1.
DR GeneID; 100757520; -.
DR CTD; 79598; -.
DR eggNOG; KOG0531; Eukaryota.
DR GeneTree; ENSGT00910000144283; -.
DR OMA; AYWRGFY; -.
DR OrthoDB; 2881819at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR GO; GO:0005814; C:centriole; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:1902018; P:negative regulation of cilium assembly; IEA:Ensembl.
DR GO; GO:1901673; P:regulation of mitotic spindle assembly; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45973:SF9; CENTROSOMAL PROTEIN 97KDA, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT REGION 648..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 583..610
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 829..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 96435 MW; F8F4F36B1FD42C0F CRC64;
MAVARADGAL APGEGSVVNW SGQGLQKLGP NLPCDADVHT LILDKNQIIK LENLEKCKQL
IQLSVANNRL VRMMGVAKLT QLRVLNLPHN SIGCMEGLKD LVHLEWLNLA GNNLKTMEQI
NSCTALQHLD LSDNNIPQIG DLSKLMSLKT LLLHGNIITS LRMAPSYLPR SLSILSLAEN
EIRDLNEISF LASLSELEQL SVMNNPCVMA TPSIPGFDYR PYIVSWCLNL RVLDGYVISQ
KESLKAEWLY SQGKGRAYRP GQHIQLVQYL ATVCPLTSAL GLQTAEDAKL EKILSKQRFH
QRQLMNQSQN EELSPLASVE TRVPLTPERS SPVQDFQESE PVLQINSWVG ISSNDGQLYA
VKSNFPASAH PTRYSRNDLH LEDIQTDEDK LNCSLLSSES TFMPVASGLS PVSPTVELRL
QGINLGLEDD DDVADESMKR MESQDLDKDK EKPLWDTNES SVQMLKSKMR KEVNENSGLL
PCTKSVLINA ILKEDNHGLT SFPEAVGHSA SHIDPNGEET ISPTASEKSP CKILTQRHVA
LGQDKVTLQK LNAAATKLQA CWRGFYTRNY NPQAKGVRYE IRLRRMQEHI VCLTDEVRRL
RKERDEERVK TFVQEEAVRF LWNEVRSLQA WQQTVEQRLI SWQTDMPSVS STLVSPKPPF
PQHQGPSSDQ SSDWFLAEDE APQEKSVPEF PDSGFHSSLT DQVHCLKDSL DFEKSSIESS
ESSMLGNSTD TVKHGRHPNL EAMTEEHGDC SKESSNSEQD NTLLEQYLSS VQQLDDAEER
TDSDDVAGDS MCHVACSPDD VAGDSTCHVA CSPEGLDASS HSEAHRESPT LQDGISQTPE
NCELSADVQG QPQESDATFQ VLHVGVTV
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