ID   G3HSU0_CRIGR            Unreviewed;      1174 AA.
AC   G3HSU0;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Protein FAM135B {ECO:0000313|EMBL:EGV96293.1};
GN   ORFNames=I79_013937 {ECO:0000313|EMBL:EGV96293.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV96293.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -!- SIMILARITY: Belongs to the FAM135 family.
CC       {ECO:0000256|ARBA:ARBA00007949}.
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DR   EMBL; JH000674; EGV96293.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3HSU0; -.
DR   STRING; 10029.G3HSU0; -.
DR   PaxDb; 10029-XP_007636945-1; -.
DR   eggNOG; KOG2205; Eukaryota.
DR   InParanoid; G3HSU0; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022122; DUF3657.
DR   InterPro; IPR007751; DUF676_lipase-like.
DR   InterPro; IPR044294; Lipase-like.
DR   PANTHER; PTHR12482:SF3; PROTEIN FAM135B; 1.
DR   PANTHER; PTHR12482; UNCHARACTERIZED; 1.
DR   Pfam; PF12394; DUF3657; 1.
DR   Pfam; PF05057; DUF676; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          943..1107
FT                   /note="DUF676"
FT                   /evidence="ECO:0000259|Pfam:PF05057"
FT   REGION          339..361
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          576..629
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          705..727
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..354
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..623
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1174 AA;  129240 MW;  DAFDBCBF027D0CE0 CRC64;
     MISSRTLGLH FHPRRGLHHQ VPVMFDYFHL SVISVTIHAA LVALQQPLIS FARPGRGSWL
     GKGGPDTGPE QPIISLENLV FGAGYCKPTS SEGSFYVPSE NCIQHAHKWH RDLCLMLLHA
     YQGLRLYFLV IMRDIPELPT MELEALDVEE TLSQLCSELQ VRRFSEAFFY MEHQKLAVLT
     FQENLIQTHS QLSLDIRNSE YLTSMPPLPA ECLDIDGDWN TLPVIFEDRY VDCPVSGHNL
     SVDPNFDVPV TSTATMNLKE KEKNVINEKS SLGKDLPLST TNTPQLGSDE NVISCSETEE
     NVSTQNPVDV CSESQVYLTI GEFQNKAVMP KDECWTGPRP VRDSDVDMHR SPCPEDGKTP
     ALTYIDVKSS NKNHPRAEPI QGLNVHHEHI RSRESYDLVK TLPNKIVAGI SQNNAINLNQ
     TAALDFRTLG RGADQEGKPV LLSLKLTPAE PFDPLNTALR EPLNNMSSLQ DSTEEQEDLS
     VLSGIIKRSA SIISDSGIDS EPSSVALSEA RSRVLDLPSD REVLHKVVQR YAHHRNSLEG
     GHTESNTSLP SGIQASLTSI SSLPFEDEER ELALTKLTKS VSAPQISSPE DTTEDADTMK
     NTGGFSEDIS SKDNNSPRHS FHSYGGSRVQ DVRAGHSLAD IAIDSDRPQG PGYIDIPKGK
     VNQSDLQGPC SLGGMAENPP SVETKGLNLK IPCTIVLENS RTRSVHRGAV GTTKGKPKES
     SGGKHILPNN SILEARAVSH HRVPEISSSS AVEAVNLIST GVQNGSSSVN DTMTLNRRHN
     ASLEVSQEAG TVCPSVTHSI ASQMSRNQEM KTGTSISGSH LNSAEAFTLD SLKAVEVVNL
     SVSCTATCLP FSSVPKEPPA RAGLSSKQSL SPITHQPLGS FGVVSTHSRK LEEVSERMLS
     FYQAKEKLKK ELKIEGFLYS DLSELASDIP YFPPEEEEEN LEDGIHLVVC VHGLDGNSAD
     LRLVKTFIEL GLPGGKLDFL MSEKNQMDTF ADFDTMTDRL LDEIIQHIQL YNLSISRISF
     IGHSLGNIII RSVLTRPRFR YYLNKLHTFL SLSGPHLGTL YNNSTLVSTG LWLMQKLKKS
     GSLLQLTFRD NADLRKCFLY QLSQKTGPVY AEMINNLLGP LVEAKGCTLI RHNVFHALPN
     TANTLIGRAA HIAVLDSELF LEKFFLVAGL NYFK
//