ID G3HTB4_CRIGR Unreviewed; 975 AA.
AC G3HTB4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Seizure 6-like protein {ECO:0000313|EMBL:EGW07185.1};
GN ORFNames=I79_014136 {ECO:0000313|EMBL:EGW07185.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW07185.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH000692; EGW07185.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HTB4; -.
DR STRING; 10029.G3HTB4; -.
DR PaxDb; 10029-XP_007627354-1; -.
DR eggNOG; ENOG502QVYR; Eukaryota.
DR InParanoid; G3HTB4; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF8; SEIZURE 6-LIKE PROTEIN; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 3.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 890..912
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 202..310
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 312..371
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 373..483
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 486..547
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 549..660
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 687..746
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 748..811
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 815..876
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 202..229
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 373..400
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 717..744
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 975 AA; 106372 MW; DCD37F0D524C073F CRC64;
MMDPNSSEKR NKGNGGPEGD THPSTAYLLP SASLESNLEE EVTSAAPGPL PSQKALETLE
GSLPPAVPDE ASVQHTPALR KNLPSLKQLN SARRQLRPLA TPTTLQRLGS STSATTKPHV
PGDAEQPTAP APLQIVPFTT LVTTLPNSPE PAQSPDDSSP GSPMDKGDNE LTGSASEESQ
ETTTSTIITT TIITTEQAPA LCSVSFSDPE GYMDSSDFPP QPLGSFLECT YNVTVYTGYG
VELQVKSVNL SEGELLSIRG VDGPTLTVLA NQTLLVEGQV IRSPTNAISV YFRTFQDDGL
GTFQLHYQAF MLSCSFPRRP EAGDVTVMDL HSGGVAHFHC HLGYELQGAK TLTCINASKP
HWSSQEPVCS APCGGAVHNA TIGRVLSPSY PGNTNGSQLC VWTIEAPEGQ KLHLHLERLM
LQEKDRMIVY SGLTNTSALL YDSLRTESVP FEGLLSEGSS IRIEFTSDQG QAASAFNIRF
EAFEKGHCYE PYIQNGNFTT SDPTYNIGTI VEFTCDPGHS LEQGPAVIEC VNVRDPYWND
TEPLCRAMCG GELSAVAGVV LSPNWPEPYA EGEDCVWKIH VGEEKRIFLD IQFLNLSNSD
ILTIYDGDEV VPHVLGQYFG NSSPQKLYSS TPDLTIQFHS DPAGLIFGKG QGFIMNYIAT
VHLTRSLKLL SPNLRKMFCF KEVSRNDSCS DLPEIQNGWK TTSHTELVRG ARITYQCDPG
YDIVGSDTLT CQWDLSWSSD PPFCEKIMYC TDPGEVEHST RLISDPVLLV GTTIQYTCSP
GFVLEGSSLL TCYSRETGTP IWTSRLPHCV SEESLACDNP GLPENGYQIL YKRLYLPGES
LTFMCYEGFE LMGEVTIRCI LGQPSHWSGP LPICKVAEAA AESSLEGGNM ALAIFIPVLL
ISLLLGGAYI YVTRCRQYSS LRLPLMYSHP YSQITVETEF DNPIYETGVK AEAPQKTPVV
MAIVPVSKMF LLPWQ
//
