ID G3HUX6_CRIGR Unreviewed; 1870 AA.
AC G3HUX6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=C-myc promoter-binding protein {ECO:0000313|EMBL:EGW10969.1};
GN ORFNames=I79_014747 {ECO:0000313|EMBL:EGW10969.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW10969.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000758; EGW10969.1; -; Genomic_DNA.
DR STRING; 10029.G3HUX6; -.
DR PaxDb; 10029-XP_007608144-1; -.
DR eggNOG; KOG2127; Eukaryota.
DR InParanoid; G3HUX6; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.100.10.50; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR018798; MVB12A/B.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR NCBIfam; TIGR00756; PPR; 1.
DR PANTHER; PTHR12296:SF16; C-MYC PROMOTER-BINDING PROTEIN; 1.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF10240; DUF2464; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS51498; MABP; 1.
DR PROSITE; PS51375; PPR; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 42..200
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 192..650
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REPEAT 818..852
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REGION 728..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1225..1250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1295..1335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1396..1420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..945
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1327
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1396..1417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1870 AA; 209938 MW; 907B9782D1C9CB41 CRC64;
MIEDKGPRVA DYFVVAGLTD VSKPLEEEIH FNDACHKVAK PKEPITDVSV VIKSLGEEVP
RDYTCIDVTP TGLSADLNNG SLVGPQIYLC YKRGRDKPPL TDLGVLYDWK ERLKQGCEII
QSTPYGRPAN ISGSTSSQRI YITYRRASEN MTQNTLAVTD ICIIIPSKGE SPPHTFCKVD
KNLNNSMWGS AVYLCYKKSV AKTNTISYKA GLICRYPQED YESFSLPESV PLFCLPMGAT
IECWPPNSKY PLPVFSTFVL TGASAEKVYG AAIQFYEPYS EENLTEKQRL LLGLTSLVDG
KSDSSRTIHT NKCICLLSHW PFFDAFRKFL TFLYRYSISG PHALPIEKHI SHFMHKVPFP
SPQRPRILVQ LSPHDNLILS QPVSSPLPLR QVKLHFCFGG KFSTLLQNLG PENAVTLLVF
AVTEHKILIH SLRPSVLTSV TEALVSMIFP FHWPCPYVPL CPLALADVLS APCPFIVGID
SRYFDLYDPP PDVSCVDLDT NTISQTGDKK NVAWKILPKK PCKNLMNTLN NLHQQLAKLQ
QRPRDEGLMD LAMNDYDFNS GKRLHMIDLE IQEAFLFFMA SILKGYRSYL RPITQAPSET
ATDATSLFAL QAFLRSRDRS HQKFYNMMTK TQMFIRFIEE CSFVSDKDAS LAFFDDCVDK
VDMDKSGEVR LIELDASFKS EHTVFVTPPE IPHLPNGEEP PLQYSYSGFP VLRNNLFERP
EGFLQARKNK LPSKPSSPRS PSPMFRRTKQ EIKSAHKIAK RYSSIPQMWS RCLLRHCYGL
WFICLPAYVK VCHSKVRALK TAYDVLKKMQ LKKMDPPDEV CYRILMQLCG QYDQPVLAVR
VLFEMQKAGI DPNAITYGYY NKAVLESTWP SRSRSGYFLW TKVRNVVLGV TQFKRALKKH
PHLSQRDLSG GRSDLGYNSL SKDDVRKEGT STEDIQGEKE KKGSDSSSFS IFLSSIFILK
YVRLRAFLCT FCNVYFNFLN IFIFIFIVSE NESTKGSADC LPTLSYQSSS TIVRLSSANN
NSADKIAGEC EESTPELLLM PSLEATNETQ NMQSRCFRKR HKSDDESHLQ QQMPWGNRNR
NLSGGVLMGF MLNRINQETS PGDMVEKLGA DAKILSNVIS KSTRPNSLDI GKPPVKSKRD
SLEKESSDDD TPFDGSNCLD KVDSPVIFDL EDLDTETDGS KVGCVAAQNP KRLQRMNSSF
SVKPSEKTDV VTGFDPLSLL VAETEQKQKV KEEEDDDDSK SISTPSAKRN LAEEIEMYMN
NMSSPLTSRT PSIDLQRACD DKLVNKKSPT LVKACRRSSL PPNSPRPVRL TKSKSYTKSE
ERPRDRLWSS PAFSPTCPFR EGTQETLAHS SPSFNLDTLL VPKLDVLRHS VFSAGKGVAE
KASKWYSRFT MYTSSKDQSS DRTSLSSVGA QDSESTSLTD EDVCHELEGA TSSQESSATS
GTKGIDVSRT SLGSSASLEG SLSKFALPGK SETASSLNTS TTNIFQNYAM EVLISSCSRC
RTCDCLVHDE EIMAGWTADD SNLNTTCPFC GNLFLPFLNV EIRDLRRPGR YFLKSSSSTE
TMHFASSFSN QTRQSCISAS ASGLDTSTLS VQGNFDLNNK SKLQENPCAR SIQIPAHRSK
TVVSKCPLFP MARSISTCGP LDKDDPGGQK LIPTGSLPAT LQGATDSLGL EWHLPSPDPV
TVPYLSPLVV WKELESLLEN EGDHAITVAD FVDHHPIVFW NLVWYFRRLD LPSNLPGLIL
SSEHCNKYSK IPRHCMSEDS KYVLIQMLWD NMKLHQDPGQ PLYILWNAHT QKYPMVHLLQ
KSDNSFNQEL LKSMVKSIKM NDVYGPMSQI LETLNKCPHF KRQRSLYREI LFLSLVALGR
ENIDIGNSLL
//
