ID G3HVM0_CRIGR Unreviewed; 285 AA.
AC G3HVM0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=H1.8 linker histone {ECO:0000313|Ensembl:ENSCGRP00001027511.1};
DE SubName: Full=Histone H1oo {ECO:0000313|EMBL:EGW12631.1};
GN ORFNames=I79_015018 {ECO:0000313|EMBL:EGW12631.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW12631.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW12631.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001027511.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; JH000781; EGW12631.1; -; Genomic_DNA.
DR STRING; 10029.G3HVM0; -.
DR PaxDb; 10029-XP_007626152-1; -.
DR Ensembl; ENSCGRT00001031758.1; ENSCGRP00001027511.1; ENSCGRG00001024504.1.
DR eggNOG; KOG4012; Eukaryota.
DR GeneTree; ENSGT00940000160900; -.
DR OMA; KMGPPMA; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR GO; GO:0001674; C:female germ cell nucleus; IEA:Ensembl.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; ISS:CAFA.
DR GO; GO:0031492; F:nucleosomal DNA binding; ISS:CAFA.
DR GO; GO:0030527; F:structural constituent of chromatin; ISS:CAFA.
DR GO; GO:0040029; P:epigenetic regulation of gene expression; ISS:CAFA.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51504; H15; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 1..75
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT REGION 61..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 31300 MW; 16CF20ABF66BE329 CRC64;
MLRMVLEALQ AREKRQGTSV VAIKVYIQHK YPTVDTSRFK YLLKQALDTG MRRGLLTRPA
NSKAKGATGS FKLVPRPKKK RTCTSIARRR ATDAKETGPK KPREPKTDHT SKAKVEKVAV
KPRPRRKACP CPAATLEKAP KKASKAKLGE VTKDPLKPDK ATLPPPTANK IGQNVKHSGN
RHESEAHGKT KDVWEKSEPS VCKVPKSAAS LTKRKMTAMA HTKTVVQGAR MVHKTKAPVP
PQDMGHKAQP TSRVRKTKSP EDPKRPGLPP KISSKAPSKK AEPGN
//
