ID G3HW08_CRIGR Unreviewed; 1047 AA.
AC G3HW08;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=MKL/myocardin-like protein 1 {ECO:0000313|EMBL:EGW02871.1};
GN ORFNames=I79_015155 {ECO:0000313|EMBL:EGW02871.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW02871.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000810; EGW02871.1; -; Genomic_DNA.
DR RefSeq; XP_007646252.1; XM_007648062.1.
DR RefSeq; XP_016833648.1; XM_016978159.1.
DR AlphaFoldDB; G3HW08; -.
DR STRING; 10029.G3HW08; -.
DR PaxDb; 10029-XP_007619889-1; -.
DR eggNOG; KOG0901; Eukaryota.
DR InParanoid; G3HW08; -.
DR OMA; SQPPCQL; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF6; MYOCARDIN-RELATED TRANSCRIPTION FACTOR A; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 3.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 96..121
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 140..165
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 184..209
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 466..500
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 226..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 880..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 642..680
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 226..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..822
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..926
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1047 AA; 111231 MW; F9EB693856937036 CRC64;
MLCRAVHLQV TVTKAKVDFS SVVCLPPSVI AVNGLDGGGC GENDDEPVLL SLSAAPSPQS
EAVANELQEL SLQPELTLGL HPGRNPNLPP LSERKNVLQL KLQQRRTREE LVSQGIMPPL
KSPAAFHEQR RSLERARTED YLKRKIRSRP ERSELVRMHI LEETSAEPSL QAKQLKLKRA
RLADDLNEKI AQRPGPMELV EKNILPVESS LKEAIIVGQV NYPKVADSSS FDEDSSDALS
PEQPASHESQ GSVPSPLESR VSEPLPSATS TSPTQVLSQL PVGPDPGEAL FLAEQPPLPP
TPLLPPSLTN GTAVPTAKPA PTLIKQSQPK SASEKSQRSK KAKELKPKVK KLKYHQYIPP
DQKQDKGAPA MDSSYAKILQ QQQLFLQLQI LNQQQQQQQQ QHYNYQAILP APPKPAGETP
GSCAPTPSRS LSTSSSSSSG TPGPSGLARQ NCTALVGKPG ALPANLDDMK VAELKQELKL
RSLPVSGTKT ELIERLRAYH DQVSPAPGAP KAPATTSLLS KAGEVVVAFP AARLSTAPAL
VTAGLAPAEM VVATVTSNGM VKFGSTGSTP PVSPTPSERS LLSTGDENST PGDAFGEMVT
SPLTQLTLQA SPLQILVKEE GARAASCCLS PGARAELEGL DKDQMLQEKD KQIEELTRML
QQKQQLVELL RLQLEQQKRA QQPAPASSPV KRESSFSSCQ LSCQPQDSPR AFGPGLVVPT
TNHGDAQAPA PGPLPVVVKQ EAGPPEPDLA SAPQLLLGPQ GTSFLKRVTP PTVVTDSTGT
HLILTVTNKS ADGPGLSTGS PQQTLSQPGS PAPGPPAQMD LEHPPQPSFA APTSLLKKEP
PGYEESVSQQ PKQQENGSSS QQMDDLFDIL IQSGEISAYF KEPPSLPGKE KPPPTAACGS
LLTPQPSPSP SNELPQAAPP PASPTLPGRL EDFLESSTGL PLLTSGHEGP EPLSLIDDLH
SQMLSSSAIL DHPPSPMDTS ELHFAPEPSS GMGLDLADGH LDSMDWLELS SGGPVLSLAP
LSTAAPSLFS TDFLDGQDLQ LHWDSCL
//
