ID G3HW43_CRIGR Unreviewed; 391 AA.
AC G3HW43;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Rho GTPase-activating protein 9 {ECO:0000313|EMBL:EGW02274.1};
GN ORFNames=I79_015191 {ECO:0000313|EMBL:EGW02274.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW02274.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000814; EGW02274.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HW43; -.
DR STRING; 10029.G3HW43; -.
DR InParanoid; G3HW43; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF103; RHO GTPASE-ACTIVATING PROTEIN 9; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 209..390
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 391 AA; 43887 MW; 640FA265CFCEC007 CRC64;
MASLKPCFLK PLKKGLRERS PSQEGSVTEA SAVMGLSSLS RSSAWGDLSD HRAALESCPA
LPHLDDPHEE MSGLINMTKI AQGGRKLRKN WGPAWVVLTG NSLVFYRERP PQCAPSQGWD
RENPLELRLS GSGPAELAEL SAGEDDELES EPVSKPLNWL SSRRVSSRSA EGTEQKNRVR
NKLKRLIAKR PTLQSLQERG LFRDQVFGCQ LESLCQREGD TVPSFVRLCV EAVDKKERAV
TSDGRYMFPE QPGQEGKLDL DSAEWDDIHV VTGALKLFFR ELPQPLVPTP LLPHFRDALE
LSEPDQCLSE MKKLVDLLPK PNRDTLQYIL EHLCRVIAHS DENRMTAHNL GIVFGPTLFR
PEQETSDMTA HVFYPGQLIQ LMLNNFDSLF P
//
