ID   G3I2V3_CRIGR            Unreviewed;       571 AA.
AC   G3I2V3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Histone deacetylase 10 {ECO:0000313|EMBL:EGW01040.1};
GN   ORFNames=I79_017747 {ECO:0000313|EMBL:EGW01040.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW01040.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; JH001148; EGW01040.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3I2V3; -.
DR   STRING; 10029.G3I2V3; -.
DR   eggNOG; KOG1343; Eukaryota.
DR   InParanoid; G3I2V3; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   PANTHER; PTHR10625:SF18; POLYAMINE DEACETYLASE HDAC10; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          34..330
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   571 AA;  61559 MW;  B0AD56EC5DB2466A CRC64;
     MDQSDHGVAM GTALVYHEDM TATRLLWDDP ECEIECPERL TAALDGLRQR GLEQRCLCLS
     ACEASEEELG LVHSPEYIAL VQRTQTLAKE ELQEMSKQFD AVYFHPSTFH CARLAVGAAL
     QLVDAVLTGA VHNGLALVRP PGHHSQKAAA NGFCVFNNVA IAAKHAKQKY GLQRILIVDW
     DIHHGQGIQY IFDDDPSVLY FSWHRYEHGR FWPFLQESDA CAVGQGQGQG FTVNLPWNQV
     GMGNADYLAA FLHVLLPLAF EFDPELVLVS AGFDSAIGDP EGQMQATPEC FAHLIQLLQV
     LAGGRICAVL EGGYHLESLA QSVCMMVQTL LGDPTPPLLG LMVPCQRFED WRVDVAPVLS
     PSTHLPEGRS LSLLAESTTC EVAEAAPSPL LDGLCLRPIP PVCTAVALTV PGAALALPPG
     VLYQEGSALR EETEAWARPH KSLFQDDGLA ALGKILCLVG GILDGQTTGG FLSCILGLVL
     PLAYGFQPDM VLMALGPAHG LQNAQAALLA AVLRGPAGGR ILAIVEEVLH QDRALQSLEI
     SQGGRFLFGE ERTQAGDRCP ICAPDILPLE Q
//