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Database: UniProt
Entry: G3I4K4_CRIGR
LinkDB: G3I4K4_CRIGR
Original site: G3I4K4_CRIGR 
ID   G3I4K4_CRIGR            Unreviewed;       274 AA.
AC   G3I4K4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   10-APR-2019, entry version 40.
DE   SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|EMBL:EGW06367.1};
GN   ORFNames=I79_018386 {ECO:0000313|EMBL:EGW06367.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06367.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W.,
RA   Xie M., Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B.,
RA   Koh W., Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J.,
RA   Quake S.R., Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell
RT   line.";
RL   Nat. Biotechnol. 29:735-741(2011).
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DR   EMBL; JH001255; EGW06367.1; -; Genomic_DNA.
DR   RefSeq; XP_003510183.3; XM_003510135.3.
DR   STRING; 10029.XP_007608930.1; -.
DR   PRIDE; G3I4K4; -.
DR   Ensembl; ENSCGRT00000013588; ENSCGRP00000013379; ENSCGRG00000009718.
DR   Ensembl; ENSCGRT00001001018; ENSCGRP00001000994; ENSCGRG00001000769.
DR   GeneID; 100757246; -.
DR   KEGG; cge:100757246; -.
DR   CTD; 9973; -.
DR   InParanoid; G3I4K4; -.
DR   KO; K04569; -.
DR   OrthoDB; 1527306at2759; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:InterPro.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IEA:Ensembl.
DR   CDD; cd00305; Cu-Zn_Superoxide_Dismutase; 1.
DR   CDD; cd00371; HMA; 1.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   InterPro; IPR024134; SOD_Cu/Zn_/chaperone.
DR   InterPro; IPR018152; SOD_Cu/Zn_BS.
DR   InterPro; IPR001424; SOD_Cu_Zn_dom.
DR   PANTHER; PTHR10003; PTHR10003; 1.
DR   Pfam; PF00403; HMA; 1.
DR   Pfam; PF00080; Sod_Cu; 1.
DR   PRINTS; PR00068; CUZNDISMTASE.
DR   SUPFAM; SSF49329; SSF49329; 1.
DR   SUPFAM; SSF55008; SSF55008; 1.
DR   PROSITE; PS50846; HMA_2; 1.
DR   PROSITE; PS00087; SOD_CU_ZN_1; 1.
DR   PROSITE; PS00332; SOD_CU_ZN_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001075};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00280};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN       20     75       HMA. {ECO:0000259|PROSITE:PS50846}.
FT   METAL        22     22       {ECO:0000256|PROSITE-ProRule:PRU00280}.
FT   METAL        25     25       {ECO:0000256|PROSITE-ProRule:PRU00280}.
SQ   SEQUENCE   274 AA;  29281 MW;  725312C94CEA5729 CRC64;
     MASDSRDGGT MCALEFAVQM TCQSCVDAVH KTLKGVAGVQ SVEVQLENQM VLVQTTLPSQ
     EVQALLESTG RQAVLKGMGS GQLQNLGAAV AIVESSNTIR GVVRFLQLTS ELCLIEGTID
     GLEPGLHGFH VHQYGDLTRD CNSCGDHFNP DGTSHGSPQD TDRHRGDLGN ILADADGRAT
     FRIEDKQLKV WDVIGRSLVV DEGEDDLGQG RHPLSKITGN SGKRLACGII ARSAGLFQNP
     KQICSCDGLT IWEERGRPIA GEGRKDSAQP PAHL
//
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