ID G3I5B0_CRIGR Unreviewed; 467 AA.
AC G3I5B0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Carnitine O-palmitoyltransferase 1, liver isoform {ECO:0000313|EMBL:EGW12712.1};
GN ORFNames=I79_018654 {ECO:0000313|EMBL:EGW12712.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW12712.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; JH001291; EGW12712.1; -; Genomic_DNA.
DR AlphaFoldDB; G3I5B0; -.
DR STRING; 10029.G3I5B0; -.
DR InParanoid; G3I5B0; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 2.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF74; CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM; 1.
DR Pfam; PF00755; Carn_acyltransf; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGW12712.1}.
FT DOMAIN 1..204
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT DOMAIN 232..439
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
SQ SEQUENCE 467 AA; 53666 MW; FF5E0EB50ED118B7 CRC64;
MVNSNYYAME MLYFTPTHIQ AARAGNTIHA MLLYRRKVDR EELKPIRLLG STIPLCSAQW
ERLFNTSRIP GEETDTIQHI KDSRHIVVYH RGRYFKVWLY HDGRLLRPRE LEQQMQQILD
DPSEPQPGEA KLAALTAADR VPWAKCRQTY FARGKNKQSL DSVEKAAFFV TLDESEQGYR
KEDPETSIDS YAKSLLHGQC FDRYLLPLIS KYVMATDVFQ LGYAEDGHCR GETNPNIPRP
TRLQWDIPGE CQEVIETSLN SASLLANDVD LHSFPFDYFG KGLIKKCRTS PDALIQLALQ
LAHYKDMGKF CLTYEASMTR LFREGRTETV RSCTTESCNF VMAMVDPTKT VEQRLKLFKI
ACEKHQHMYR LAMTGAGIDR HLFCLYVVSK YLAVDSPFLK EVLSEPWRLS TSQTPQQQVE
LFDFEKHPDY VSCGGGFGPD SHRFGKHVKQ AMIDIINLFG LTVNSKK
//
