ID G3I7H6_CRIGR Unreviewed; 769 AA.
AC G3I7H6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Zinc finger protein 43 {ECO:0000313|EMBL:EGV93056.1};
GN ORFNames=I79_019465 {ECO:0000313|EMBL:EGV93056.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV93056.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH001432; EGV93056.1; -; Genomic_DNA.
DR AlphaFoldDB; G3I7H6; -.
DR PaxDb; 10029-XP_007614056-1; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; G3I7H6; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 16.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24376; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24376:SF238; ZINC FINGER PROTEIN 594-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR SMART; SM00355; ZnF_C2H2; 15.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 16.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 1..43
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 260..287
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 316..343
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 369..396
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 397..424
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 425..452
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 453..480
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 481..508
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 509..536
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 537..564
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 565..592
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 593..620
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 621..648
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 649..676
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 677..704
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 705..732
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 733..752
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 769 AA; 89213 MW; 7E0DC773F00F30A1 CRC64;
MLENYRNLVF LGLAVSKPYL VTCLEQRKEP WNVKRQKTMV LFPAMFPHYD QDFSPEQNIK
YSFQELINGS HRNYGLDNVY FGEERESIEG CEVQKTYDNG HNHNQFVIAC NRSFTPSREQ
DHEMAQENCH TMSVTCEQPC TSVSKHQNHL FKCTSSFKDN LGNLQRDLIH SSVNDFNNFK
CSFGLSFHSN IFVDGELKNE EKISKCDQFE NSIVKNSLVY DQQIGLSCAK TQNFHKYGRF
FTHPVLPNQN SNTDILEIQY ICKENRKAFT EESTLSNHEG TYIGETVYQC NENDSDLTHE
SNPANHQSAH FPKNFYKCYK CDTVFHQYSE LIIHQYIHIQ DQISKGMDCN PAFNKSSSLT
RSHTGEKPYK CKECGKAFTY CSSLRQHHRI HSGVKHHKCK ECGKAFYHKS LLTQHQSIHA
GKKPYCCKFC GKAFNQRSTV TQHQRIHTGE RPYHCKDCGK AFHQRSSLSL HQRVHTGEKP
YKCKECGKAF NRNSLLTQHQ RIHTGEKPYH CKDCGKAFNK KSSLTQHQRI HTGEKPYSCK
DCGKAFNQRS SLSLHQRGHT GEKPNKCNEC GKAFNRVFFL TQHQKIHTGE KAYHCKDCGK
AFKQRSSLTQ HQRVHTGDKP YLCKHCGKAF TQRSSFTRHQ RIHTGEKPYK CQDCDKAFSR
NLLLIQHQRI HTGEKPYHCQ DCGRAFNQRS SLTQHQRVHT GDKPFCCKDC GKAFTQRSSF
NRHQRIHTGE KLYKCKECDS TFNCSSHLAE HQCTSLGSCF QDTKFLQFM
//
