ID G3I8S0_CRIGR Unreviewed; 372 AA.
AC G3I8S0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Rab9 effector protein with kelch motifs {ECO:0000256|ARBA:ARBA00039295};
GN Name=Rabepk {ECO:0000313|RefSeq:XP_027279514.1,
GN ECO:0000313|RefSeq:XP_027279515.1, ECO:0000313|RefSeq:XP_027279516.1,
GN ECO:0000313|RefSeq:XP_027279517.1};
GN ORFNames=I79_019948 {ECO:0000313|EMBL:EGV94256.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV94256.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGV94256.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_027279514.1, ECO:0000313|RefSeq:XP_027279515.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027279514.1,
RC ECO:0000313|RefSeq:XP_027279515.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_027279514.1,
RC ECO:0000313|RefSeq:XP_027279515.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Rab9 effector required for endosome to trans-Golgi network
CC (TGN) transport. {ECO:0000256|ARBA:ARBA00037224}.
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DR EMBL; JH001529; EGV94256.1; -; Genomic_DNA.
DR RefSeq; XP_003511477.1; XM_003511429.3.
DR RefSeq; XP_007623551.1; XM_007625361.2.
DR RefSeq; XP_007623552.1; XM_007625362.2.
DR RefSeq; XP_007650136.1; XM_007651946.2.
DR RefSeq; XP_007650137.1; XM_007651947.2.
DR RefSeq; XP_007650138.1; XM_007651948.2.
DR RefSeq; XP_027279514.1; XM_027423713.2.
DR RefSeq; XP_027279515.1; XM_027423714.2.
DR RefSeq; XP_027279516.1; XM_027423715.2.
DR RefSeq; XP_027279517.1; XM_027423716.2.
DR STRING; 10029.G3I8S0; -.
DR PaxDb; 10029-XP_007623551-1; -.
DR GeneID; 100755498; -.
DR KEGG; cge:100755498; -.
DR CTD; 10244; -.
DR eggNOG; KOG0379; Eukaryota.
DR InParanoid; G3I8S0; -.
DR OMA; CTPGSIW; -.
DR OrthoDB; 5474681at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP001108280; Chromosome 6.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011498; Kelch_2.
DR PANTHER; PTHR46647; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR PANTHER; PTHR46647:SF1; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF07646; Kelch_2; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 372 AA; 40432 MW; 3DA4E1D8745AE415 CRC64;
MKQLPVLEPG DKPRKATWYT LTRPGDKPCP RVGHSCSYLP PAGDAKRGKV FIVGGANPNQ
SFSDVHIMDL GTQQWDTVTT EGLLPRYEHA SFIPSCTPHS IWVFGGADQS GNRNCLQVLD
PETRTWTTPE VSSPPPSPRT FHTSAAAIGN QLYVFGGGER GDQPVQDVKL HVFDANTLMW
SQPETHGSPP SARHGHVMVA TGTKLFVHGG LSGDKFFDDL HCIDISNMKW QKLSPTGAVP
AGCAAHAAVA VGKHVYMFGG MTPSGALNTM YKYHTEKQHW TSLQFDTFLP PGRLDHSMCV
IPWPVMSTSE NEDSDSVILK CEAEKGDAAD IQVAQGGGLP EESQTNMLLC FVFGGMNTEG
EIYDDCFVTV VD
//
