ID G3I9G9_CRIGR Unreviewed; 679 AA.
AC G3I9G9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=FERM domain-containing protein 6 {ECO:0000313|EMBL:EGW06497.1};
GN ORFNames=I79_020216 {ECO:0000313|EMBL:EGW06497.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06497.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH001604; EGW06497.1; -; Genomic_DNA.
DR AlphaFoldDB; G3I9G9; -.
DR STRING; 10029.G3I9G9; -.
DR PaxDb; 10029-XP_007629834-1; -.
DR eggNOG; KOG4371; Eukaryota.
DR InParanoid; G3I9G9; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13185; FERM_C_FRMD1_FRMD6; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR041781; FRMD6-FERM_C.
DR InterPro; IPR047145; FRMD6-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR13429; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR PANTHER; PTHR13429:SF11; FERM DOMAIN-CONTAINING PROTEIN 6; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 76..388
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 424..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 679 AA; 78507 MW; 21474E9A9E7BB032 CRC64;
MNKLTFHNNR VMQDRRSVCI FLPNDESLNI IIKLALECWD PERLLSTRCA QPTFWRAHNT
MNKLTFHNNR VMQDRRSVCI FLPNDESLNI IINVKILCHQ LLVQVCDLLR LKDCHLFGLS
VIQNNEHVYM ELSQKLYKYC PKEWKKEASK VRQYEVTWGI DQFGPPMIIH FRVQYYVENG
KLISDRVARY YYYWHLKKQV LHSQCVLREE AYFLLAAFAL QADLGNFKRN KHRGKYFEPE
AYFPAWVVSK RGKEYILKHI PNMHKDQFAL TASEAHLKYI KEAVRLDDVA IHYYRLYKDK
REVEASLTLG LTMRGIQIFQ NLEEEKQLLY DFPWTNVGKL VFVGKKFEIL PDGLPSARKL
VYYTGCPTRS RHLLQLLSNS HRLYMNLQPV LRHLRKLEEN EEKKQYRESY ISDNLDLDMD
QLEKRSRASG SSAGSVKHKR LSRHSTASHS SSHTSGIEAD TKPRDPGPED SCSGSAMHRK
LKTCSSMTSH GSSHTSGVES GGKERLEEDS QDDEIEMLVD DPTDLEPMTE EVSPDVCIYI
TEDMLLSRKL NGHSGLIVKE ISSSTSSSSE TVVKLRGQST DSLPQTICRK PKTSTDRHSL
SLDDIRLYQK DFLRIAGLCQ DTAQSYTFGC GHELDEDGLY CNSCLAQQCV NIQDAFPVKR
TSKYFSLDLT HDEVPEFVV
//
