ID G3IAV7_CRIGR Unreviewed; 547 AA.
AC G3IAV7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Carboxypeptidase N subunit 2 {ECO:0000313|EMBL:EGW12890.1, ECO:0000313|Ensembl:ENSCGRP00001009449.1};
GN Name=Cpn2 {ECO:0000313|Ensembl:ENSCGRP00001009449.1,
GN ECO:0000313|RefSeq:XP_035299991.1};
GN ORFNames=I79_020739 {ECO:0000313|EMBL:EGW12890.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW12890.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW12890.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001009449.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_035299991.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_035299991.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_035299991.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; JH001760; EGW12890.1; -; Genomic_DNA.
DR RefSeq; XP_003512114.1; XM_003512066.1.
DR RefSeq; XP_007630977.1; XM_007632787.1.
DR RefSeq; XP_035299991.1; XM_035444100.1.
DR STRING; 10029.G3IAV7; -.
DR PaxDb; 10029-XP_007630977-1; -.
DR Ensembl; ENSCGRT00001013663.1; ENSCGRP00001009449.1; ENSCGRG00001011563.1.
DR KEGG; cge:100770664; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000163072; -.
DR OrthoDB; 5397075at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR Proteomes; UP001108280; Chromosome 4.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR46473:SF13; APPLE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46473; GH08155P; 1.
DR Pfam; PF13855; LRR_8; 4.
DR SMART; SM00364; LRR_BAC; 7.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000313|EMBL:EGW12890.1,
KW ECO:0000313|RefSeq:XP_035299991.1};
KW Hydrolase {ECO:0000313|EMBL:EGW12890.1, ECO:0000313|RefSeq:XP_035299991.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Protease {ECO:0000313|EMBL:EGW12890.1, ECO:0000313|RefSeq:XP_035299991.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..547
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041117349"
FT DOMAIN 21..53
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 395..446
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 547 AA; 61133 MW; 7F3EE3BBBE9AD56A CRC64;
MFPGSWLCWA SLLLLARPTQ SCPMGCDCFD REVFCTDQQL ATIPLDIPSH VTDIVFVETT
FTTVETRAFS NNSNLTKVVF LNTLVCHLEP DAFGGLPRLE DLELTGSSFS NLSADIFSNL
SSLGKLTLDF DRLVALPEDL FHHMDNLESL QLQGNQLQTL PGRLFQPLRY LRTLNLDQNF
LNKLPKGLFQ SLTNLQILKL SNNMLTSLPE GLLADLGSLQ ELFLDSNAIE ELSPQVFSQL
LSLEKLWLQH NAISRLPDSV FSSLYNLTFL NLQDNALWTL PADLFTHTSR LLYLSLSYNQ
LETITEGTFA NLSRLVFLTL SHNAITYLPK DVFRDLKQLV RLFLNSNNLT ALHSALFQNL
SRLELLNLSK NQLTMLPGGI FDTNYNLFNL ALFGNPWQCD CHLAYLASWL RLYSEGIFNR
DTYCAGPAYL KGQLVPSLKQ EQLVCPVTPG HLGFLAPGLD DREPGGSWDL AVEGRAAHSQ
CTYSNPEGTV VLACEEAQCR WLSIRLSSRQ GSDSPAMAYN SSQEWELRSN CGSMRVVVSI
EAQAAGP
//
