ID G3ITT7_METTV Unreviewed; 1035 AA.
AC G3ITT7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:EGW22608.1};
GN ORFNames=Mettu_1423 {ECO:0000313|EMBL:EGW22608.1};
OS Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylobacter.
OX NCBI_TaxID=697282 {ECO:0000313|EMBL:EGW22608.1, ECO:0000313|Proteomes:UP000004664};
RN [1] {ECO:0000313|EMBL:EGW22608.1, ECO:0000313|Proteomes:UP000004664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1195 / DSM 17260 / SV96
RC {ECO:0000313|Proteomes:UP000004664};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Held B.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N.,
RA Ovchinnikova G., Pagani I., Klotz M.G., Dispirito A.A., Murrell J.C.,
RA Dunfield P., Kalyuzhnaya M.G., Svenning M., Trotsenko Y.A., Stein L.Y.,
RA Woyke T.;
RT "Genomic sequence of Methylobacter tundripaludum SV96.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH109152; EGW22608.1; -; Genomic_DNA.
DR RefSeq; WP_006890578.1; NZ_JH109152.1.
DR AlphaFoldDB; G3ITT7; -.
DR STRING; 697282.Mettu_1423; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_6; -.
DR OrthoDB; 9758297at2; -.
DR Proteomes; UP000004664; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004664};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 349..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 869..888
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 895..915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..942
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..992
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 998..1023
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1035 AA; 111976 MW; 687412281EE61B39 CRC64;
MRSSALGSFA TRHGLVIAFL CVALCLAGAY AALGMPSSIF PQTNFPRVVI LIDNGVMPAN
EMMATITRPV EEAMKDIPGV RTVRSKTGRG SAEINVFFTW QTDMVQAELF VQGRLAVVQK
TLPATASSAV WRLTFAAFPV VGLSLTGPAH SLTELWETAR YTIGPRLLRI PGVARTGIVG
GRAPEYHVIV DPLRLQAVNL SLAQVTDALV RNNLIAPTGM LEEDYKLYLT VVDGRVHTVE
DIQNLTVSVT GNTPIAGAAQ AVASGAHPIR IKDFARVERS QEPAFNIVTA NGVNAVLLNV
YSQPDGSTLD IAKQLKQELE SLKKALPPGM QASVFYDQSL LVGDSIRSVW EAILLGLILS
VIILYVFLKN WGATLIAAMV IPATVLITLL MLRIMGLGFN LMTLGGIAAA IGLIIDDAIV
VVEAVHTKIT AGEQRLAAVQ QALTDIFRPL LASTLTPVVV FIPLAFLDGV AGCFFRALAL
TMVVSLLTSL VLAVTLIPSL AVWWMPTDRQ SPSSAKANWL ERLIQNYEKV LRTALKQAGK
VLTGCVLILA LGVWLYGRLE SEFLPFMDEG GFVLDYRAPW GTSLAETDRQ LRQAETLLRA
MPELESYSRR TGARLALGIS QAHMGDFLVK LKPDRQRKTD EVVADLRKQL HVAVPGIEWE
FAGILNDLIG DLTWSPRPIE IKLFSTDVEW LKQKAPQVEA ELKKIDGVVD TFDGLETTGP
SLSLHVRDSD AQRFGLTVND VALAVGTAML GQKASHVLEG DRVVNIRVRM NTGTTGQIAS
LRELPLRSLD GRTVKLSQVA DVVTEPGQLE LHREDLRQLV AVSARLENRD LGSAITEIKA
KLGRDQTLPP GVLEFGGLYQ QQQESFHNLL LVLLASIFLV FTVLLVEFGS FYEAIAIVFG
SVLALCGTVL AWYLTGTSVN IVSLLGAIIG IGVVAKNGIL MLDSVHRFES QGVTLENALV
ESGRRRLRPV LMTSLAAALG LVPLAYGIGA GSDMLKPLAI AVIGALTLSV LLSLVATPTV
YFAMRRLGKK FDDTL
//
