ID G3J3N8_CORMM Unreviewed; 730 AA.
AC G3J3N8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Potassium channel, putative {ECO:0000313|EMBL:EGX95714.1};
GN ORFNames=CCM_00368 {ECO:0000313|EMBL:EGX95714.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX95714.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX95714.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX95714.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|RuleBase:RU003857}.
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DR EMBL; JH126399; EGX95714.1; -; Genomic_DNA.
DR RefSeq; XP_006665591.1; XM_006665528.1.
DR AlphaFoldDB; G3J3N8; -.
DR GeneID; 18162403; -.
DR KEGG; cmt:CCM_00368; -.
DR VEuPathDB; FungiDB:CCM_00368; -.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_013394_0_0_1; -.
DR InParanoid; G3J3N8; -.
DR OMA; SFEEWAW; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:EGX95714.1};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 52..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..298
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 384..455
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 515..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 82186 MW; E7D3937282B8563C CRC64;
MTAAASSSSP PGAGKQEEDP AEGAAAAPEA EDPARAQVSE PNEEENLNHT RWWLVASAFP
MIAGTLGPVA SAFSICALSR PWRQYMPPGT DFESATYVSD PPWLTAVNAV QLAMAVVSNV
FLLLNMARRV KFTIAQPITI VGWYISSFCL IALCATASGP LKQGLDNPVK DYVLSQAFYY
GIWAAILYFV VASFMTATFW GASTGHFSKS FALTSSQRTL MLQTILFLTY LLLGALIFST
IEGWNYLDGV YWANVTLFTV GFGDFAPTRS LARALLLPYA LIGIVSLGLV IASIRSMILD
RARRRVAIRM EEKTRRRLVR TLTKTGNDTI LRPMSGGDED ASLSPHVTNE YERRKVEFEL
MRSIQDRALR RRQWMDLSAS FGTLIVLWLV GALVFWMTEK DYQENWTYFI AFYLCFVSLT
TIGYGDRVPI TNAGKAFFVF WSLLALPTMT VLISHAENTV VKFVKEMTIK LGAVTILPRD
KIIAQMEKEH LKQYNSHQTP GLRLDAGGLV RWRSRSHSRS KHVSPDGRAH GTDDPDAEPG
TLRTRRRRAA RHTHLRSVAT RLRHAAQIQG QHLHQHQNRP LDTLPTGHEF QLLLVAEIRA
VTQHLREATP RRYSFEEWAW FLWLLGEDER DAHTHRKARP DEKRTHHGVA EQPRKLHADG
TLHSAQPFQW SWVGSRSPLT ADQEESEWVL DRLTFRLQKA LENDADTEEA AAAAAKRCLA
PDTELQIRRS
//
