ID G3JGJ8_CORMM Unreviewed; 221 AA.
AC G3JGJ8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Hsp70 nucleotide exchange factor (Fes1), putative {ECO:0000313|EMBL:EGX92415.1};
GN ORFNames=CCM_03788 {ECO:0000313|EMBL:EGX92415.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX92415.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX92415.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX92415.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
CC -!- FUNCTION: Functions as a nucleotide exchange factor (NEF) for Hsp70
CC chaperones which accelerates the release of ADP. Required for fully
CC efficient Hsp70-mediated folding of proteins.
CC {ECO:0000256|ARBA:ARBA00024912}.
CC -!- SIMILARITY: Belongs to the FES1 family.
CC {ECO:0000256|ARBA:ARBA00011045}.
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DR EMBL; JH126401; EGX92415.1; -; Genomic_DNA.
DR RefSeq; XP_006668999.1; XM_006668936.1.
DR AlphaFoldDB; G3JGJ8; -.
DR STRING; 983644.G3JGJ8; -.
DR GeneID; 18165811; -.
DR KEGG; cmt:CCM_03788; -.
DR VEuPathDB; FungiDB:CCM_03788; -.
DR eggNOG; KOG2160; Eukaryota.
DR HOGENOM; CLU_084507_0_0_1; -.
DR InParanoid; G3JGJ8; -.
DR OMA; QNNEKTQ; -.
DR OrthoDB; 5473057at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR013918; Nucleotide_exch_fac_Fes1.
DR PANTHER; PTHR19316:SF18; HSP70-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR19316; PROTEIN FOLDING REGULATOR; 1.
DR Pfam; PF08609; Fes1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 6..98
FT /note="Nucleotide exchange factor Fes1"
FT /evidence="ECO:0000259|Pfam:PF08609"
FT REPEAT 144..172
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 221 AA; 23270 MW; 4C8E1B5353A44F03 CRC64;
MGDKRLNELL RWSIENTETE QPNGTGAVAT TGEGASAAPV SNLTPEVMAA LMGGPSDADL
MIASMEIITA ADVTLENKLI AFDNLEQLIE SLDNANNLAS LGLWTPLLAQ LASPEAEIRT
MAAWCIGTAV QNNEKTQERL FAVGGVPPLV ALATSPDETD TVRRKAVYAL SSAIRNYQPA
LDAAVVELVA AGHPADKVDA MDMEAVDTII TPLREKAMAA A
//
