ID G3JQS2_CORMM Unreviewed; 559 AA.
AC G3JQS2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Acetamidase {ECO:0000313|EMBL:EGX89098.1};
GN ORFNames=CCM_07350 {ECO:0000313|EMBL:EGX89098.1};
OS Cordyceps militaris (strain CM01) (Caterpillar fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=983644 {ECO:0000313|EMBL:EGX89098.1, ECO:0000313|Proteomes:UP000001610};
RN [1] {ECO:0000313|EMBL:EGX89098.1, ECO:0000313|Proteomes:UP000001610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM01 {ECO:0000313|EMBL:EGX89098.1,
RC ECO:0000313|Proteomes:UP000001610};
RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116;
RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., Huang Y.,
RA Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.;
RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, a
RT valued traditional Chinese medicine.";
RL Genome Biol. 12:RESEARCH116.1-RESEARCH116.21(2011).
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DR EMBL; JH126404; EGX89098.1; -; Genomic_DNA.
DR RefSeq; XP_006672554.1; XM_006672491.1.
DR AlphaFoldDB; G3JQS2; -.
DR STRING; 983644.G3JQS2; -.
DR GeneID; 18169361; -.
DR KEGG; cmt:CCM_07350; -.
DR VEuPathDB; FungiDB:CCM_07350; -.
DR eggNOG; KOG1212; Eukaryota.
DR HOGENOM; CLU_009600_9_2_1; -.
DR InParanoid; G3JQS2; -.
DR OMA; EPWRPEM; -.
DR OrthoDB; 731186at2759; -.
DR Proteomes; UP000001610; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR PANTHER; PTHR46072:SF11; AMIDASE-RELATED; 1.
DR PANTHER; PTHR46072; AMIDASE-RELATED-RELATED; 1.
DR Pfam; PF01425; Amidase; 1.
DR PIRSF; PIRSF001221; Amidase_fungi; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001610}.
FT DOMAIN 104..547
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
FT ACT_SITE 159
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 234
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 258
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT BINDING 208
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 234
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
FT BINDING 255..258
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-2"
SQ SEQUENCE 559 AA; 60573 MW; 3181336AC61AEA43 CRC64;
MGTATESQQA YILNAKTEDR RPATESPAPI WENIGARKRA LLSASIPEEW RVPATLLPPD
AQDDVTTWPA TSGWFTQAEL DITEQTATQL VAKLTTGALS SETVTRAFCK RAAAAHQLVN
CLSETCFERA LATARARDAH FAKTGQPVGP LHGLPISLKD NFKLAGLDST VGFSSHVGDA
AADDSMLAKV LEEAGAVFYV KTNVPTAMMI AETINNVFGR TLNPRNRQTT SGGSSGGESA
LLVLNGSPIG VGTDIGGSLR IPAACTGIFT LRPSVGRFPV RDCRSGMPGQ EGVMSVNGPM
ARTLADIALY SRVVVQGRPW LRDAKCLPLP WQPRAAPPTL RIGVMWDDTL VRPTPPVARA
LRHTVARLLR AGHDVVDWRP TDMLQSLTMI SRFFVADGAA AIRKELARTG EPWRPEMDAY
RDAQPMSVFD VWSLQTERTA FQNANLDRWN EAGLDALLLP TMPYVTHRHN GTRHVAYTAI
VNILDVSAVS FPTGLTVDKT IDVVGPEYEA LSDTCEAIHA EYDSDLLDGM PISLQLVARK
LEEEQVLGMT ESVLQALSD
//
