ID G3LX04_9CAUD Unreviewed; 609 AA.
AC G3LX04;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AEM91719.1};
GN Name=45 {ECO:0000313|EMBL:AEM91719.1};
GN ORFNames=PERSEUS_45 {ECO:0000313|EMBL:AEM91719.1};
OS Mycobacterium phage Perseus.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Fromanvirus; Fromanvirus perseus.
OX NCBI_TaxID=2922996 {ECO:0000313|EMBL:AEM91719.1, ECO:0000313|Proteomes:UP000008526};
RN [1] {ECO:0000313|EMBL:AEM91719.1, ECO:0000313|Proteomes:UP000008526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22282335; DOI=10.1128/JVI.06870-11;
RG the Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science Program;
RG the KwaZulu-Natal Research Institute for Tuberculosis and HIV Mycobacterial Genetics Course Students;
RG the Phage Hunters Integrating Research and Education Program;
RA Hatfull G.F.;
RT "Complete Genome Sequences of 138 Mycobacteriophages.";
RL J. Virol. 86:2382-2384(2012).
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DR EMBL; JN572689; AEM91719.1; -; Genomic_DNA.
DR RefSeq; YP_009016031.1; NC_023720.1.
DR GeneID; 18563995; -.
DR KEGG; vg:18563995; -.
DR OrthoDB; 14842at10239; -.
DR Proteomes; UP000008526; Segment.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Reference proteome {ECO:0000313|Proteomes:UP000008526};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 15..192
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT DOMAIN 372..555
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 609 AA; 67586 MW; E47CE15A39CB9F2D CRC64;
MKQHRYQIKD ETVLVNVVEH EDDLDGFESF IRSNLRILGL DTETTDLGIY KPDFGIRLIQ
FGNPWESWVL PVERGGVFVG AAVTALQKVQ RFVIHNAAFD LQVIERTLGV PMEQMWPKVE
DTKIYSHLVD PRAYKEGGTG HKLEELTKFY IDPVTAEEVK ASMARLAKKH KTTKDKIWAL
VDLNDPDYEL YAGMDTILVS RLLGKVAPLV PESSHKLIPY EHKLAEVMSY VERTGFLLDV
DYSEKLSADM LRKSEHYTAV ARYAYGVDSV NSTEKLADGL ERTGVKIKGR TATGKRQVNA
ELLEALAEEG NALAKAAIEA KKWGSWEKTW VRNFIERRDA NDRVHPGINP LQARTGRMST
SNPSAQNLPS GDWMVRRCFL ADPGQIIASV DYRAQELRVL AALSGDQTML RAFEEESDLH
QVTADAAGVD RKIGKMANFL VCYGGGAGKL ATNAGITFPE AKKVLEVFAT TYPGVDTLNK
RMQQEAGSAG FITTPTGRRL PVDPDRAYSA LNYLIQSSSR DVTGAAVLRL HEAGFTPNMR
LVVHDEVLLS LPEADAESAV KEVGQIMEQR IGPVLVNTDP EATGKSWGSG YMDAETMAQH
DAELRSRGF
//
