ID G3MXT0_BOVIN Unreviewed; 351 AA.
AC G3MXT0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=MAF bZIP transcription factor A {ECO:0000313|Ensembl:ENSBTAP00000054350.1};
GN Name=MAFA {ECO:0000313|Ensembl:ENSBTAP00000054350.1,
GN ECO:0000313|VGNC:VGNC:31138};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000054350.1, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000054350.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054350.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000054350.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054350.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005215337.1; XM_005215280.3.
DR RefSeq; XP_015321758.1; XM_015466272.1.
DR AlphaFoldDB; G3MXT0; -.
DR SMR; G3MXT0; -.
DR STRING; 9913.ENSBTAP00000054350; -.
DR PaxDb; 9913-ENSBTAP00000054350; -.
DR Ensembl; ENSBTAT00000037397.5; ENSBTAP00000054350.1; ENSBTAG00000026344.5.
DR CTD; 389692; -.
DR VEuPathDB; HostDB:ENSBTAG00000026344; -.
DR VGNC; VGNC:31138; MAFA.
DR eggNOG; KOG4196; Eukaryota.
DR GeneTree; ENSGT00940000162747; -.
DR HOGENOM; CLU_063062_0_0_1; -.
DR InParanoid; G3MXT0; -.
DR OMA; GAHHTAH; -.
DR OrthoDB; 5399309at2759; -.
DR TreeFam; TF325689; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000026344; Expressed in longissimus thoracis muscle and 36 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030073; P:insulin secretion; IBA:GO_Central.
DR GO; GO:0007263; P:nitric oxide mediated signal transduction; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0009749; P:response to glucose; IBA:GO_Central.
DR CDD; cd14718; bZIP_Maf_large; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR004826; bZIP_Maf.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR013592; Maf_TF_N.
DR InterPro; IPR008917; TF_DNA-bd_sf.
DR InterPro; IPR024874; Transcription_factor_Maf_fam.
DR PANTHER; PTHR10129; TRANSCRIPTION FACTOR MAF; 1.
DR PANTHER; PTHR10129:SF30; TRANSCRIPTION FACTOR MAFA; 1.
DR Pfam; PF03131; bZIP_Maf; 1.
DR Pfam; PF08383; Maf_N; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF47454; A DNA-binding domain in eukaryotic transcription factors; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 252..315
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 40..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..208
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 36952 MW; 0C5C0CAB885BA7F7 CRC64;
MATELAMGAE LPSSPLAIEY VNDFDLMKFE VKKEPPEAER FCHRLPPGSL SSTPLSTPCS
SVPSSPSFCA PSPGTSGGAG GGGGAAQAGA TPGQASGGPG AVGGASGKPA LEDLYWMSGY
QHHLNPEALN LTPEDAVEAL IGSGHHAGHH GAHHPAAAAA YEAFRGQGFA GGGGADDMGA
GHHHGTHHAA HHHHHAPHHH HHHHHGGAGH GGGGTTHHVR LEERFSDDQL VSMSVRELNR
QLRGFSKEEV IRLKQKRRTL KNRGYAQSCR FKRVQQRHIL ESEKCQLQSQ VEQLKLEVGR
LAKERDLYKE KYEKLAGRGG PGGAGGAGFP RESSPPQAGP GGAKGAPDFF L
//
