ID G3MZ72_BOVIN Unreviewed; 520 AA.
AC G3MZ72;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=FERM domain containing 1 {ECO:0000313|Ensembl:ENSBTAP00000054866.2};
GN Name=FRMD1 {ECO:0000313|Ensembl:ENSBTAP00000054866.2,
GN ECO:0000313|VGNC:VGNC:56363};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000054866.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000054866.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054866.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000054866.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054866.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005199549.1; XM_005199492.3.
DR RefSeq; XP_005211218.1; XM_005211161.3.
DR RefSeq; XP_010797372.1; XM_010799070.2.
DR RefSeq; XP_010797373.1; XM_010799071.2.
DR RefSeq; XP_010797374.1; XM_010799072.2.
DR RefSeq; XP_010807064.1; XM_010808762.2.
DR RefSeq; XP_010807065.1; XM_010808763.2.
DR RefSeq; XP_010807067.1; XM_010808765.2.
DR AlphaFoldDB; G3MZ72; -.
DR SMR; G3MZ72; -.
DR STRING; 9913.ENSBTAP00000054866; -.
DR PaxDb; 9913-ENSBTAP00000054866; -.
DR Ensembl; ENSBTAT00000064655.2; ENSBTAP00000054866.2; ENSBTAG00000014062.6.
DR GeneID; 616869; -.
DR KEGG; bta:616869; -.
DR CTD; 79981; -.
DR VEuPathDB; HostDB:ENSBTAG00000014062; -.
DR VGNC; VGNC:56363; FRMD1.
DR eggNOG; KOG4371; Eukaryota.
DR GeneTree; ENSGT00940000162787; -.
DR InParanoid; G3MZ72; -.
DR OMA; SYGCVYS; -.
DR TreeFam; TF319780; -.
DR Proteomes; UP000009136; Chromosome 9.
DR Bgee; ENSBTAG00000014062; Expressed in cortex of kidney and 24 other cell types or tissues.
DR GO; GO:0098592; C:cytoplasmic side of apical plasma membrane; IBA:GO_Central.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0035332; P:positive regulation of hippo signaling; IBA:GO_Central.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047145; FRMD6-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR13429; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR PANTHER; PTHR13429:SF7; FERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 6..310
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 330..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 58443 MW; 377A62DD00AFFAA3 CRC64;
MTAELRDVLV LLPMREQLRL AVGVQATGRE LLQQVCDQTG IREAHFFGLS VVRNNEHVFM
DLEQKLSKYF SKDWKRETCG GRGRPGAPFV AFLGVQYYVE NGRLIRDRAA RHLYYLQLKE
RVLRSQCAHR EEAYFLLAAY GLQADLGDHR RLAHAGRYFQ PQTYFPQWLI AKRGSAYVLR
HAPALHREQR GLSPREAELR FIREACRLED VPVHFFRLYK DKKEDRPTVV LGLTLRGLQV
FQEVNHTPQL LYDFPWPHVE KLAFLGKRFE LWPHGQPAAR RLVYHTGCAW RSRHLLRLLR
TSHQLHLGLQ QARQQLQLLE EAEEKQCYRE SYVSDARDGN QDPEPAGSGD HAGPDQRPLS
LCSLLSAGSC CSSHAPAFEV DPQRAGPEEP GEMSVDEPEG VAALPTEEPP CSPSTSRSSP
GCGGRASPQQ PLAVVQVTLV SMRAPSAEAT LHQVLEAKAA AGHADQHSRS LGHTRPEPAP
RPAPRSRALG RALDSGPRGS VNSLSPSRLQ KDQLPEEFVV
//
