ID G3N208_BOVIN Unreviewed; 534 AA.
AC G3N208;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Butyrophilin like 9 {ECO:0000313|Ensembl:ENSBTAP00000055913.2};
GN Name=BTNL9 {ECO:0000313|Ensembl:ENSBTAP00000055913.2,
GN ECO:0000313|VGNC:VGNC:109404};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000055913.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000055913.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055913.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000055913.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000055913.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR AlphaFoldDB; G3N208; -.
DR Ensembl; ENSBTAT00000064130.2; ENSBTAP00000055913.2; ENSBTAG00000047420.2.
DR VEuPathDB; HostDB:ENSBTAG00000047420; -.
DR VGNC; VGNC:109404; BTNL9.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000160338; -.
DR HOGENOM; CLU_013137_7_4_1; -.
DR TreeFam; TF317532; -.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000047420; Expressed in bone marrow and 103 other cell types or tissues.
DR ExpressionAtlas; G3N208; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF141; BUTYROPHILIN-LIKE PROTEIN 9; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..534
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018534333"
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..150
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 158..244
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 312..509
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 341..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 60498 MW; 10745475E1764C85 CRC64;
MDFSVFLNSY QRGRLPSSLF FLTHLLLLLQ PRVLCSEEIR VVGHEEPILA HVGDEVEFSC
HLSPYRDAQH MEILWFWSQA SNVVHLYREQ QEFYGWQMKQ FQNRTQLIRD DIIDGSVTLR
LHLVVPADQG LYGCRFLSSD FTGEATWELE VAGLGSDPHI SIEGFKEGGI QLRCHSNGWY
PKPQAQWRDR HGRCLPPETE NITEDVQGLF SLETSVVVQE GAHSNVSCSI QNHLLGQKKE
FVVHIADVFL PGTSPWKRAF LGTLVGLPLL LALLMMLVLY FFRKQRKSQE KLKKQAERDK
GKFAYQGRGQ GCGWGQNRPW RALTLCLCAV DVTLDPGSAH PSLEVSEDGK SVSSLRTAPG
SENPQWLSEQ TCVLSRELFS TGRHYWEVHV GRRSRWFLGV CLAAVPRAGH ARMSPATGYW
VMGLWNSCEY FVLDQHRVPL SVRVPPRCVG IFLDIEAGKL SFFNVSDGSH IFTFTDTFPG
MLCAYFRPRA HDGSEHPDPL TICPLPVGEK HVLEEEDSDA WLQPYESSNT DLGL
//
