ID   G3N414_GASAC            Unreviewed;       428 AA.
AC   G3N414;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Matrilin 4 {ECO:0000313|Ensembl:ENSGACP00000000031.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000031.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000000031.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000000031.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3N414; -.
DR   Ensembl; ENSGACT00000000031.1; ENSGACP00000000031.1; ENSGACG00000000022.1.
DR   GeneTree; ENSGT00940000157086; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000000022; Expressed in embryo and 2 other cell types or tissues.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   CDD; cd00054; EGF_CA; 1.
DR   Gene3D; 2.10.25.10; Laminin; 4.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR   Pfam; PF14670; FXa_inhibition; 3.
DR   Pfam; PF00092; VWA; 2.
DR   PRINTS; PR00907; THRMBOMODULN.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00181; EGF; 4.
DR   SMART; SM00179; EGF_CA; 4.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF57196; EGF/Laminin; 3.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS01186; EGF_2; 3.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   DOMAIN          23..199
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          371..428
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   428 AA;  47050 MW;  F7CF77E04C00322C CRC64;
     LLVLASARPK AGPEQKCKSG PVDLVFLIDS SRSVRPHEFE TMRKFMIDIL STLDIGLNAT
     RVGVVQYSSQ VRSEFSLKTH PGLDAMVKGI NEIIPLAQGT MTGLAIKYVM NSAFIDEEGD
     RPKVPNVAVI VTDGRPQDRV AEVAAEARGK GIEIYAVGVA RADMASLRAM ASPPFEDHVF
     LVESFDLIHQ FGLQFQDKLC GVDLCLESEH SCEHICESSP GSFHCLCLPG YTLREDGKTC
     AAIDLCAEER HDCEQICVTS PGSFTCDCNK GFKLDEDKKS CTMIDYCSFG NHSCDHECEG
     VLNGYFCRCH QGYRLLDAKR CEDMDLCSSV QHGCEHQCVS TPGSFYCVCP EGQLLQEDGQ
     SCGSCKSANI DLVLLIDGSK SVRPQNFELV KKFVNQVVDS LDVSAQGTRV GLVQYSSRVR
     TEFPLNRH
//