ID G3N4Q3_GASAC Unreviewed; 1601 AA.
AC G3N4Q3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313|Ensembl:ENSGACP00000000273.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000273.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000000273.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000000273.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR STRING; 69293.ENSGACP00000000273; -.
DR Ensembl; ENSGACT00000000273.1; ENSGACP00000000273.1; ENSGACG00000000209.1.
DR eggNOG; KOG0401; Eukaryota.
DR GeneTree; ENSGT00940000154648; -.
DR InParanoid; G3N4Q3; -.
DR OMA; EEGFYKW; -.
DR TreeFam; TF101527; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000000209; Expressed in liver and 12 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF10; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 1242..1364
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1434..1600
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 738..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1040..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1095..1242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..49
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..342
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..440
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1073
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1601 AA; 176980 MW; B892D59C1A9AE8FD CRC64;
MNKAPQPLTG PPSNPHPAPS PGLSQPRSPQ APPFRVFATP PPPQMTPAPQ PRQGSFRPLQ
SELPSPPLSQ CMCPMALGPP PHSGPRPVTP THVYQPGPGS QMMMIPGQQL PFQSSPQGPA
YFIPGQYRSA TYVATPQQYP VPAGTPGFYP GTSPADYGSY AGAYYPAQPQ FNPSLQPAPV
IMSPAPLPQP PQHIATKRER KQIRIRDPNQ GGRDITEEIM SGGRSGSTPT PPQFNGESVP
AAASPALVRP DRPDERGKPT PPPSKTPELV KGDPVPTEAS ASDTNTKPPA PPLLSEPQEV
PVHTAPARAP VPDVMDAPRA PREAPPHPQS APEVPAYPAP LPATIPAAAQ SKADKKTTEE
LKEVKKEEKA AAPPVAPPCA ANGVAEVEHE RPAAASPPPS CHLESPPESP IAQPEELRLP
NGLPLPAEVP AHPVVPAEPP RPEVQDEVAP DITEETPVPA ALAAATEEMQ SPEETVPEET
VPAETVPAET VPEDTVPEET LPEETLPEEA AMQAAVSVPK KKRKMKDLNK KEAVGDLLDA
FKEIWFLTSN LSTLEPGTSG CSTETRPPAP EEADLTWEDK EDKEGKADAE NIQPDADKKY
QYKEEQWKPI DPEQKKHYDR EFLLGFQFSS ASMSKPEGLP AISDVVLDKA NKNPLRQLDP
SRLMGMNCGP DFTPSFANLG RPGMGGGGGG GGGGSRGPPP GLGMGAGGPR RSQQMQRKEP
RKILTTMSLG DDVQLNKAEK AWKPTAKKPT RSRAAEEPEE SESEDAKTQE LFKRVRSILN
KLTPQKFQQL MKQVSELTID TEERLKGVID LTFEKAISEP DFSVAYANMC RCLMGLKVET
SDKPGTFVNF RKLLLNRCQK EFEKDKDDDE IFERMQKELE AASVPEEKQK LTDELQSAKD
QARRRSLGNI KFIGELFKLK MLTEVIMHDC IVKLLKNHDA ESLECLCRLL STIGKDLDFE
KAKPRMDQYF HQMERIIKEK KTSSRIRFML QDVLALRKNA WVSRRGDQGP KTIDQIHKDA
ELEEHREQMK VQQALIFKKE RMGGGGRGGG RNNPPQDEGW NTVPISKNRP IDTSRLSKIT
KTPVLDFNNQ LLAPGGKGTW GSWGKGSSGG SSAKPAEAGS EAGGRPATST VNRFSALQQS
APPSGSAQDA DRRVPQRNSS SRERGDRFER RDDRDRNRLQ VTKRSFSREN SERSREREQR
GSADPVRRVA SMTDDRGSRD RARSKETAPP QTPAKPALTE EELSKKSTAI IEEYLHINDM
KEALQCVQEM NSTQLLSVFV RNGLESTLER STIAREHMGL LLQQLIKAGV LPTEQYYHGL
QEILQVAEDM AIDIPHIWLY LAEQITPMLH EGGIPMGELF REVSKPLIPQ GQAGVLLVQI
LSLLCKGMSH KKAGTMWREA GLRWKDFLPE DLDVDKFVTE QNVEFTLCSE SQTKKKEELS
PAELSRHLER LIQDQADNQR IFDWIEANLD EQQTSSNMFV RAVMTCVCQA AVVCENPNKV
DGEQMKRRAK VLQRYLLDEQ KELQALYALQ ALMVQMEQPA NLLRMFFDTL YDEDVIKEEA
FYQWEASKDP AEQQGKGVAL KSVTAFFTWL RNAEDEDEDD N
//
