ID G3N5V5_GASAC Unreviewed; 6813 AA.
AC G3N5V5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Spectrin repeat containing, nuclear envelope 2b {ECO:0008006|Google:ProtNLM};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000679.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000000679.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000000679.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus outer membrane
CC {ECO:0000256|ARBA:ARBA00004605}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004605}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004605}.
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
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DR STRING; 69293.ENSGACP00000000679; -.
DR Ensembl; ENSGACT00000000679.1; ENSGACP00000000679.1; ENSGACG00000000520.1.
DR eggNOG; KOG0516; Eukaryota.
DR GeneTree; ENSGT00940000154656; -.
DR InParanoid; G3N5V5; -.
DR OMA; NEANYID; -.
DR TreeFam; TF337116; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000000520; Expressed in muscle tissue and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR CDD; cd00176; SPEC; 3.
DR Gene3D; 1.20.58.60; -; 10.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR012315; KASH.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR21524:SF5; KLARSICHT PROTEIN; 1.
DR PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF10541; KASH; 1.
DR Pfam; PF00435; Spectrin; 4.
DR SMART; SM00033; CH; 2.
DR SMART; SM01249; KASH; 1.
DR SMART; SM00150; SPEC; 12.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 9.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT TOPO_DOM 1..6762
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TOPO_DOM 6784..6813
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 4..109
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 161..267
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 6754..6813
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
FT REGION 130..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2132..2162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2315..2423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3979..4009
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4038..4064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4089..4206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4407..4437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6276..6315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6344..6365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6378..6416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6698..6727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1442..1496
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2766..2841
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3840..3895
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4566..4637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5096..5123
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5150..5177
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5417..5447
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 130..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2340..2354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2363..2377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2379..2393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4041..4061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4147..4167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6707..6727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 6813 AA; 770797 MW; 5FD3275A7B3862A4 CRC64;
EQEQIQKKTF TNWVNAQLTK RRPPCRVLDL FNDFRDGSKL LDLLEVMSGQ RLSRERGRGM
FQHRSNIEKA LSFLKSKSIK LVNINIPDII DGKPSIILGL IWTIILQYHI EELASSLSFS
SRQSSMESLA SLDSRSTRSR GSACSSPAPP RGSPLHHRFR VSAKKALLLW VREQCHRAGC
SINVKDFKAS WRSGVVFLAI LYALRPDLVD LSSARTRSNR QNLEEAFRLA ERELRIPRLL
DPDDVDVRDP DEKSIMTYVA QFLQYSKDQP VGEEETQATP TRKAQEVTCW LVQAYDELLE
GWDSTEGESY SERYHVFQTF LVSFNEQRRP IMPLLTAMRR TPQLSEEQRA LREAWDSLTE
KLREYKVELD SSLPAPLDSV AGWLLKTEKA LAEEEGDPQD HGRAAADARE RQALLKVCLE
EMPQHVRTFQ NFQNLDEDGN MMVPADKMEE LKRRFTGVRV TAKYHGIKLE YWEQRHSVLD
LLGQMRSRLR VWKRPAFSPE GVRVLLQEWH DVVKTQELPS LLEASLHKLK QVSEKYSSKS
ALDYQHVSQQ VKQLEEDTAG ALEDVTTAKS AMGRVLFAWD SYSDCLSSLQ AWMEQGSATR
GPEVTPECMA EWGSRQAHLN EMGNFLMEST DPQTSRSLAE ELRRLNLLWA EFVKTNALTK
EKPQHLRQAD PQQPRMNPVE SRETLMPKIV VQEYRDRTVA SPPMPYSYAQ AVSQTKTPPE
GHIQAWIETT GQQQQQQSRD QGVKQNQEQR NIQKEKQLQQ EAEPVQVVEM NQYQVQQQVV
TDKLTSECPE QKSLQRPHVK KQDVISQGLQ SRKTQAMKNR PWLQKPVSGE HQTPEQVSTP
ETITQTQPQS DRAVQHQQAT AQAPLYSLGQ SQGQSQGQSQ VSLKCKHKET LKTLDPELLE
EFLRAAEGME AFCTPPQLRD MEFFTQAVRT QWEAVRAEIS GFLQQLRFEV IRKDFNKAAL
QCEALLSSRL ENPAQVDQLL EPHSACFSAE GSFAQAGQHL EALEELCDTL SPEDAHRLAQ
TQLRECETRL AAIQRRFSGD QDAPLPDARS AVAFTEDVST QKATRPSDKP QVSAEVLPVT
TKSVSVEGSV EKQVSTEEDV TTKETLERYE MCKRSLQAQL AKNQQSIKDV PHDSVSLKGL
HTRLQEIQFL RQETESLWSE YSSSQVSVPG LEQEKAALQE QWRGQQSSLQ RRGSSLGAAL
RQIDSTENHM VDFTDRLDRY LRQPKDITAF TLANSNILKD IKELDDNIQS ELDQLARLDP
ESSDLDPRDC RPLSREVETH RASLDHLRQQ VRKSEAAGRA LDRFLMSLRT VDEDISGVQG
APCSNAAVLQ DCRSKLALIR QSVGSLKEKA PQLDVLLQGA RLTVTRDGVP ASCLDMVTAL
LARLQEADGG LAGQQRGLQK ETQGQSLGLR KRALLGELRK LQDAIEKRGL KEPTAPAVQH
RLRALSDLES QLQAQRAELQ NLRELQEEQG GGEHLLQELE AQWKETQRAY SDSKKQCSIL
LELLKTFHSC RSQMSSTVQK AEQTIGDQAS YLSKDNLQRR IARVRDSKEE LGVVGEHMEE
MREVCRQLQS HLKTFPDCSE TPFEAEADTL VDIWLDVTEK TDACMDNLQV GLELWEKQLV
LGGEVDDWAG AKLTLFAESH PFHNEQQVLA MRDEIQVNEE NIDHFHRKSV EIQEMLQSPE
SPLELQVTET QLRKRMEQVK ELFADCADVF EELVAVKKHL AQKIEECQSA VETIQGSVSR
VDASHATFQD QLQRQCGALE AQEEQAQAVL KEVALVSSVA SPDMLEALIE DGSRLKEALS
RTGDMIQLKR EERDKGLLKV VQAERQSFEE WFQDSQLSVN ECFESPESRA DVDTSLQRLA
GFLKSRDAER RLDQLKQQME RGGRQVPPQQ LHEFTDWLKE QQKEVATFRT HCHDRQKQLE
PLLSDLNSLQ KQHDSFREWL QNKEKQSVES LHRRSDMFHP LLLRHQAILS SKAEGDSKVD
DLRRQSESLC EQEDLEKSRK QEVQQSLRQT EEQWRTSLQT AEDFDAFKSQ SESICSWIGE
RRRQLASLGG HMQLEERLKV TQTILSCKPE GDCAVNNLRR RGQSLCDHQD VDQGRKVHVQ
KTIRDSEEQW RTVLLAAKQF FSLDPQTILS QKAEGDSKLS ELRRQSQSLS DQEEAQQALR
DTEEQWRTVL QTAERTLKKA EVHYSLSREL EAFAAELSET TQEPYWSDPS WASEEESIPP
LLKELTVSSE CKSSSIMHVD TMQKVVCRIN ATLEEGEKLR TSLREALSHQ PFLTECLMSV
LSEKLLSEGS ETLREADKHA ASLNQSLKEL DEKLSRQKVN SHQPKAIQAS TELPKTKEEE
PASTSSQTKV QASTELPKTK EEAESQTPSS TPEVGEATTK ETAVEKGELS PTKGKSKALE
TFTEPASTSS QTKDMKRPQE KPIPRLQVQR LQLPRQLPKD PQMWSPKKIL HLQMWSRSQL
IKLLWEKESL HQPKHAAPPV HRLNCFSSRH TSVPAIEDNR TLQRNKEAQL QLVSDYHRQT
QAAGTTLLRL TAELEDITTS PEESSAKDAE RLRSLQRSME EHRAVLGELL MTHARLGPNL
SWSDRAAARS EQNNLQDGWR GLERAVERTL HHTNVHSHSA SDLLLTISGL QEHLETIAKD
LESASVPQWT CESAQRLMVA NAEVKAAQLK HLHLQQLSGA FLLSSQREEE TAEIQQGLQR
VKDQLCSTEE LVSSQSRSSS SPVMEKVIQV MRDGLAWAKQ TESDIEGRRK RIALLPEEVH
RQLRDLKKLQ SEVMAKQGQL GSLAEEVEEL LPQLDPAEEV PMVRSSLKSL EEVSKSTTET
LAKAVRELES GLQTREKLSE QIVELDSWVL AHLHREASRS PDSELSNPTE LDRRIRQMLE
TQVEAEKQAA VCEALLMKSK DIASELSIPE TCQLFDKLTD LQEDIRAIGC YEKANKQEQD
DLSLAVDSSK KNLVSLETSL RQMSGDLSRH RFPITSESLQ ALEPFKDVIL EHKAQVDLLQ
PWIPREKTGE LHSVVSQLLS KIYSLEMKAR GHERYLNKRQ CVEDLRENVK EQVCQTKDKS
KPLEEKYKVC QTLLVQLPLI KYLSIEAGTQ LQGISADLYP SQQSAERQRL RNNEESLDAL
EMTLYNNLSI IEWNLLKELD LDSERASART FLHQTQQELQ KTPTLEPKET AINEQYQRTM
SLKKTVESRM RALGVLEQKK GGRPGSVSQD LVDLQVAVLS ECDSQMEEIS QAKESLRSYT
NAVKQAAEFL RNIEVSLLPP QGTAGLCSES LEETQRALAS LQQQFQTHVE ELQRQDTLHP
YLSAQRVEQL QEDILSRLLV RMSTLQAKGH MRVECLSSCA EQHRKYAARR EEILQSVQSA
ASSLSQLVRE KVSSLTDCTD QHTQLTVRMR LRPLLTTLFE VLSEEVETLQ RRLEELEEWC
PEQSCRGGRE AAVAAVWRRV SRLRRCTREL ATRSRRRVAE WIQITDGVEK ASTLLEQVEA
EHPDGSPVKA SSEDLQALLQ RWEQHQDRLD CEHRALSALE LRTARLLGVP AHLEKAPPAA
LCQQLQAMQD RYGSVKQRSR EGLKAARAEL EERERLGGEL QAVGVWLQAA DGLLSKMEKS
RSTQELQEVH SQLCNHKASL QRVTEGVKMK YSDASSPVWL EFDGRLQDVS QSLQKVQVKV
GEALEKSGPV YRLGARLSEI QAGLTSVQKR LEQRSPNVSQ AKLTQRRAWD ELDVWHSAVA
ALEVDVQDLE KPEEVLILTE RLVEVQQLHS LLAKQAEQRT SLISKIQTWL QEHQEMISSS
KSWMAEAKSW LATPCTYTTA KCLSSHVHSL QTVLDDSAQI RSALQGFGSV LKEMSQVCDV
AALQEQLDEA EVQVAVVQDG FTAPLSHLGH AAAEVEAIEI EVRRMENDVA DVNASLSSSE
ALSKTARAER IRAQVIEQKI QSMRTTIAEI QKCKPGLCLP EKAEETLTVF AVVDQLQTLL
LGLEKVSTSK VPALFVQQPP APSAQTSSLP GLLKSTSEES EPENTTPPEL CFVSQDKEVE
EGQIQIVHVK EDVLKESGAS LQAVHRSSPE QRQSRSPDGT QDVSLLEGAL GGKVSHKKNK
NKKAKTFKVP LILTPEETEG GAGGSAKQTG GDREVTPSPA PLVFGGQRDN SHMGGSNSGM
FLQDVEGPTE ASSSEALSAV WPQSLPESTV DTPPPLKVST PDPGTPQRYI KAPEEEPQPG
SRPPRGGALH ACLQRVGQLE LWLQEARRSP AAMRPSVEQQ LLTCQEMFQD IERRVSCLPP
LGRPADGRQE AAELLSSKLE ALKANLVSFQ QLLQGRREPG GQVHAARTPP RVSHLNSSSQ
QFYISFTEEI FSSPRNKLLR QSSLQQQKVP DSRVEKGQPF ILLYIYNPQL FNSNYIVYNK
QTKRIVRMSL WALSHFVPLK GVGAAADGAE RTDSLHRPAG QRDSPPRPGA GGPQQAVATV
TRCTITWHHV SVNRTKRTKY SSTRRSDGTA GRVITAQTVK ELQTHISHLR ELRLTAAPHR
VGARRRGNMQ RREGNVRGVE TISLSAELAT LGGELASRGS EVSRVLGAQQ CVADVCRVLP
AVRSALSSRE QQLAELQEDV TQQQILLNEL HAAFTSNQAA LLQITKESTG PPQLQALAEM
QESLQQQVEQ VSSLLEEAGR PHLPAALLQQ ASHLQAALVG SLGGVGSLRE ELEAGVELQQ
QCERLVGGLE ELLALGSERL ARRPVAELQT SARLQRQLAG HTGFFRFLGH RFQILQQLTQ
RVPKSAQRRW EAAVTGLQAE VSRMQQHALD EGTRMQETLQ MWSLWEEDSA WTDSLLRDIE
TSFPKMHEGD NSELGAYQER RGVLQGSRAR FSRMLEAGLW LKVAGCGGVG ASTRSLEARW
RALHRKVELK HTDVERRRKL RSRFCRDSAA LAEWMGGARE LIDQCRQLSA EDEVDVEQRR
DHYLKSVTLT KELEAKSQLK AAVVCVGTQL VELREEDRDP DGGLEDPDRL PVPSQLRRVE
LHWSGLQADA PVLQRALHER WMKTLSQQEA LLELQAWLEV AESRLEEHRG RVNGSSASDA
DLGRLLRCCE ESRAEMTAHR ATLDYLSRPL HTCGTEDGQR GRQEHNQFAE EQGRLNHRWL
RLLETLDCQL DEVQQEMRSR AEQEARLQQI NSWIADQNRW MDSARTPSSL TELQRSVDAA
QDLQEKIEHR AAALQESRGR LVGGGTSSRD LIARTEKSIQ ACAALTQQVN DPQDNKLLRA
QQLWECVPKP LNQMMLKTAR VSQTLELHSG AALCLQAHRD LHLQLQLLHE ETEASGTEWD
GLSRSASTLS GLISPAAGVL LMEQLDKQRD RRLRGSRAVL QLWEAYGALA ASSSLRLRAL
RTEERLLLNH CLSLSPSVPQ GLLERTDALQ SDMGGLLEAS RDLTGHLEAS AASLVQSESW
LLSHGVQQLS RALTGSRTQL QEELEQLQEF EDVLEALEEK LELQQQVRLR PSSLCKSGLL
ELSAASADLD VLNGRSCSLS LGDAAAHRLR SLNRRWADAS ARAEEACSEL QAEALRQQSF
QEKCESWMSF LQRMEDSLAV DVSGSYVGLR QQLRTHKVLN AELSTGHQIL HSVISEALHL
LQRGEVEDRS DFVLKLSQLR EHWQGAVRRA EQRRSWVEGL VEHWHVFGRS LRKLRRFLSS
PRQLRSSLRG LQITAFFTAY MQMTLIEMYR NHAEQMFQRH QCSFIHTLEV GRQLFSMGDE
ETQTRLQSDL GTLQEEWDGL HGLLGRRTEL TEEVVKTWER CEAGLADVAL QLEELKTRLN
QSMPESDEEL LRADRNNKEN EDALEDWAES LTELSTMKTD LSQYVIADDV LLLQEQVEHL
HRQWEELCLK VSLRKQEIAD RLNAWIIFNE KNQELCEWLT QMENKVAHDS DLNIEEMVEK
LKKDCMEEIN LFSENKTHLK QLGEQLITAS NKTKETQVND KLKDVNDRWQ HLFHHIEDRV
RKLKETLVTV QQLDKNMSGL RTWLSHMEAE LARPLVYSVC HGDEIQRKLA EQQDLQRDIE
QHAESVASVL TLCDVLLHDA DACGGDSESD SILQTTRSLD RRWRNICAVS TERRMRIEET
WRLWCKFLDD FSRFEDWLKT AELTAANPDS ANVLYTSAKD ELKRFEAFQR QVHERLTQLE
LVNKQYRRLA REHRTDAAST LRVLVHEGNR RWDGLQKRVA SVLRRLKHFT SQREDFEGRR
EAILVWLTEM DLQLTNVEHF SQSDAEDKMR QLNGFQQEIT LNTNRIDALI VFGENLIQKS
APLDAVLMED ELEELHSYCQ EVFGRVSRFH QRLVSRPVRE EERELSDPDD TADPTPGTSS
WDGEGKEEES PAVGGVSYSQ RAACHLPAPP PARPGRETPV SVESIPLEWD HTVDVGGSSS
HEDDEDAAYF SALSVKSVTD PPSWHQPAPP QSRAPFHQQG YVRTPPPPPA SPSQVKLMSE
CSGTINSVRR VKLILDHEEE PEDPGLTSST ADKQTSTGVI ERWELLRAQP LHGDGVQQDM
EQWQKLNADL CDVTSWLGRA LPELERLQRI EPSTSIRDME VNARTLKEMQ RTFNSYKCLM
ISANLSSRHF LRGDGAEQQE LRDAIDSANR GWMQACGGLE SWERRLHSAL MECQEFHEAL
HSLLLWLSRA ENTLAGVDVV DQQRDTLTLL SVAPCLQALQ HELRGRQREV SSLQDISSQL
LLEAPGEDSV EAKEKVHVIG NKLHLLLRRV EADLNALQER PNPKNDRPEA QNVNQEQKPD
TSLIPWQPRL SSGAAAQGTA GCSRQERRDS APQRPFFLRV LRAAFPLHLL LLLLLLVSCL
VPLSDESFSC TLSNNLARSF YPMLSYTNGP PPT
//
