ID G3N5X6_GASAC Unreviewed; 626 AA.
AC G3N5X6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Premelanosome protein a {ECO:0000313|Ensembl:ENSGACP00000000700.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000000700.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000000700.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000000700.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR AlphaFoldDB; G3N5X6; -.
DR Ensembl; ENSGACT00000000700.1; ENSGACP00000000700.1; ENSGACG00000000544.1.
DR GeneTree; ENSGT00950000183188; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000000544; Expressed in camera-type eye and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 250..281
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 626 AA; 67275 MW; FE74D97333002E49 CRC64;
IKMFSKIFSV KSSISRFVEN EPRKSEPRSQ FTRYRSWNSR KYPVWKDGDP RFRNCWLGGE
VTFDLKNDAP TLTGARATFN INLNFPQNQT TLSDGQVVWA KNCTVNGQQY QEGQAVYRDQ
DTQSTGVFPD GTPFTRSRNG KPHYVFVWKA WGRYWQVADG PSSSLTIGTE NVALGSHNME
VIIYHCRGKD KFIPLGYAST VFTITDQIPF TISLAQVNDL NQDDQNFIQN RAIAFSIKLH
DPSQYLNSAD ISFSWDFGDS TGTLISRSLT VTHTYLAVGT FNPQVVLMAN IPNGCGNPTA
APTEGGDTIA LDVPASVATP LAVSVQPAEA VDGEAVVDTD TEAVASVAPA VVDAAVVTEE
QDTTVEEAVP ADDTEAEVQA TENEVAATPA PAGTEAEVQA EVEVDPAQVA LVVAKRQAPE
LPADCMVYRY GSLATSVVVV QGIESVEIVQ MSNVVAMATE LAQNAVDVTI SCQGSLPSEV
CTVISDADCI TPMETVCSAA LPSPDCQMIL RQFFNDTGVF CINVSLTNDV SLAVTSARVS
VSVVSASGGS PGGTAATVLG VMVLACVVCC IGLMYRLFKQ YQPLREDHDD TNGGGSAVTS
MPLLLWNLLS RQSPGESRPL LQGRVV
//
