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Database: UniProt
Entry: G3N807_GASAC
LinkDB: G3N807_GASAC
Original site: G3N807_GASAC 
ID   G3N807_GASAC            Unreviewed;       412 AA.
AC   G3N807;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   18-SEP-2019, entry version 46.
DE   SubName: Full=Potassium inwardly-rectifying channel, subfamily J, member 8 {ECO:0000313|Ensembl:ENSGACP00000001441};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000001441, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000001441}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000001441}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   STRING; 69293.ENSGACP00000001441; -.
DR   Ensembl; ENSGACT00000001442; ENSGACP00000001441; ENSGACG00000001115.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193347; -.
DR   InParanoid; G3N807; -.
DR   OMA; CPTAITV; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003278; K_chnl_inward-rec_Kir6.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF11; PTHR11767:SF11; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01331; KIR61CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     71     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    147    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    175       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      183    353       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      366    390       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        162    162       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   412 AA;  46356 MW;  ED48BF778A46D1A9 CRC64;
     MLARKSIIPE EFGLPGLASR MPRKPVFRDR VNKARFIAKN GSCNLAHKNI REQGRFLQDV
     FTTLVDLKWR FTLVIFTTTF VSSWLLFAMS WWLVAFAHGD LDSARWQNKT YCVTDVKSFT
     SAFLFSIEVQ VTIGFGGRMI TEHCPTAITV LIMQNIIGLI INAVMLGCIF MKTAQSNRRA
     ETLIFSRHAV IAVRNNCLCF MIRIGDLRKS MIIGATVRLQ VVRKTTTPEG EVIPIHQIDV
     ATETAVASNS LFLLAPLIIC HVIDKNSPLY DLSAMELQCS DLEVIVILEG VVETTGITTQ
     ARTSYISEEI QWGHRFVPIV TEEEGVYSVD YSKFGNTIKV TTPRCSAREL DEKPSILIQT
     LQKSELSHQN SLRKRNSMRR NNSMRKNNSG LALPKVQFFT PAEGGQNMNA VT
//
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