ID G3NAB6_GASAC Unreviewed; 326 AA.
AC G3NAB6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=NTR domain-containing protein {ECO:0000259|PROSITE:PS50189};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000002261.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000002261.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000002261.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR AlphaFoldDB; G3NAB6; -.
DR STRING; 69293.ENSGACP00000002261; -.
DR Ensembl; ENSGACT00000002267.1; ENSGACP00000002261.1; ENSGACG00000001736.1.
DR eggNOG; KOG1366; Eukaryota.
DR GeneTree; ENSGT00940000154063; -.
DR InParanoid; G3NAB6; -.
DR OMA; CARYLEQ; -.
DR TreeFam; TF352568; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000001736; Expressed in liver and 11 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR11412:SF167; COMPLEMENT COMPONENT C3B, TANDEM DUPLICATE 1 ISOFORM X1-RELATED; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM00643; C345C; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 177..324
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
SQ SEQUENCE 326 AA; 37032 MW; 297E59A28991CD5A CRC64;
QVVTFYNQLH EVDDKTSCKD FELLVTIEES SETPPADVEK SYQMSIRVRA LGPTDVRMVV
LDISLPTGFS PETSDLEKLS NSVDRYINHF QVVDNLSDRG SLIIHLFKVS HKEPEVLIFR
LQQRFRVGLL QPSSVTVYEY YNPDHRCSHT YTPREDREEL SQICRNDACR CAQGDCCVSR
SDSENVPHQE RETFACKTLH HGIFKVKVLN VSQSYYDKYE MEITQVIKLG IEAGVEVGQR
RLFMSHGGCR DGLVLNQGSQ YLIMGPTEDQ WNADADTGRS VYVLGKDTWV ERWPSPTECS
STDGLSDKCR SLKDAATELS VNGCRL
//
