ID G3NDG6_GASAC Unreviewed; 803 AA.
AC G3NDG6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Amphiphysin {ECO:0000313|Ensembl:ENSGACP00000003366.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000003366.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000003366.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000003366.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3NDG6; -.
DR STRING; 69293.ENSGACP00000003366; -.
DR Ensembl; ENSGACT00000003377.1; ENSGACP00000003366.1; ENSGACG00000002564.1.
DR eggNOG; KOG3771; Eukaryota.
DR GeneTree; ENSGT00950000182882; -.
DR InParanoid; G3NDG6; -.
DR OMA; EXNRIAK; -.
DR TreeFam; TF313542; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000002564; Expressed in diencephalon and 4 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR003017; Amphiphysin_1.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF2; AMPHIPHYSIN; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR PRINTS; PR01252; AMPHIPHYSIN1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..244
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 731..803
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 248..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..315
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..649
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 803 AA; 86804 MW; 59316B4A24E985FF CRC64;
MAEIKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE QVVVNFRRQE SEGSRLQREM
KAYMSAIKGM QQASINLTQS LHEVYEPDWH GKDDIMVIGK DCDAMWEDFH NKLVDSTLLN
LDEYLLQFPD LKTRVAKRSR KLIDYDSARH HVETLQVSGM KNDRKMMKAD EELKKAQKVF
EELNVGLQDE LPTLWDSRVG FYISTYKSVT NLEARFHREI SHDTLQVCRQ LYEVMTQLAE
QHSDKMFTIQ GAPSDSGPLR LARTPSPTED ESPPESPDAI ANHMLRPVSP GPPRPKSPIQ
LKKGPPVPPP PKATPTKEVA EEQIINLFGG DFLPAPSLSQ QPNERPGESL LDMDFDAFQP
DESVSPIPQT AVPWDMWAAN AQTTEPAADT NFVADWSADF GSLPANEDTS PGVEAPAVGL
EGAQGRVQGG AQDLPQTDVW QPDPSLETQG GGAFDSDPFA ETQGGGAFDS DPFAETQGGV
HSLESQERGE FELDPFAETQ GGGFFDSDPL AGTQGMDSFH SDPFAETQDN FVETRIPKEP
ENSDMSEDET ANRRFDSNGP PEALVREAAD EQDKSSSPLA GEGHPSPPAG EGPPSPPAGE
GPPSPPAGES PPSPPPGEGP PSPPAGEGPP SPPAGEGPPS PPAGEGPPSP PAGEKSSSLG
SFGSSSNKSE PDEKMPIPSV VIEPASSNEG DDDRDADIIS PTAISDNGVT LENQTIKHMS
PSGGVSGLPD DFLYKVETMH DFEAANSDEL ELKRGDVVLV VPTASAEDQD AGWLTGIRES
EWLTIGAGAH RGLFPENFTQ HLE
//
