ID G3NKI7_GASAC Unreviewed; 554 AA.
AC G3NKI7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
DE AltName: Full=Nuclear protein NP60 {ECO:0000256|ARBA:ARBA00032038};
DE AltName: Full=Putative oxidoreductase GLYR1 {ECO:0000256|ARBA:ARBA00034145};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000005850.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000005850.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000005850.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
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DR AlphaFoldDB; G3NKI7; -.
DR STRING; 69293.ENSGACP00000005850; -.
DR Ensembl; ENSGACT00000005867.1; ENSGACP00000005850.1; ENSGACG00000004418.1.
DR eggNOG; KOG0409; Eukaryota.
DR eggNOG; KOG1904; Eukaryota.
DR GeneTree; ENSGT00940000156435; -.
DR InParanoid; G3NKI7; -.
DR OMA; DIGNACK; -.
DR TreeFam; TF324195; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000004418; Expressed in diencephalon and 13 other cell types or tissues.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05836; PWWP_GLYR1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR035501; GLYR1_PWWP.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 8..66
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 93..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 60925 MW; 1E253D7DEB706B31 CRC64;
MATVHLRIGD LVWGKLGRYP PWPGKVVSPP KDLKKPRGKK CHFVKFFGTE DHAWIKVEQL
KPYHAHKEEM IKINKGKRFQ QAVDAVEDFL KKAKGKEQVR SHKSQLRRQR RLKRKEDTHQ
AAEDTGGGRR GSQCPEGSLR EVPKQLFRFN VKFPSRSPPD KGSINRNEPL NKPPLDELDL
TDSDPEPSTL ERLGAGPGSG FNWESSVDSE PVKDDPHFHH FLLSQSEKPA SSMEPISKRL
KIVEEESGST SIQAADSTAI NGSITPTDKR IGFLGLGLMG SGIVSNLLKM GHVVTVWNRT
AEKCDLFIQE GARLGRTPAE VASTCDITFS CVSDPKAARD LVLGPSGVLQ GIRPGKCYVE
MSTVDPGTIT ELSQVITSRG GRFLEAPVAG SQQLSNDGML VILAAGDRTV YEDCSSCFQA
MAKTSFFLGE AGNAARMMLI LNMVQGSFMA TIAEGLTLAQ ATGQSQQTFL DILCQGQMAS
TFVDQKCQNI LQGNFKPDYY LKHIQKDLRL AISMGDKANH PTPMAAAANE VYKRAKALDQ
SDNDISAVYR AYIH
//
