ID G3NKM7_GASAC Unreviewed; 596 AA.
AC G3NKM7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Nuclear factor, erythroid 2-like 2a {ECO:0000313|Ensembl:ENSGACP00000005890.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000005890.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000005890.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000005890.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the bZIP family. CNC subfamily.
CC {ECO:0000256|ARBA:ARBA00008157}.
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DR AlphaFoldDB; G3NKM7; -.
DR Ensembl; ENSGACT00000005907.1; ENSGACP00000005890.1; ENSGACG00000004470.1.
DR GeneTree; ENSGT00950000182892; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000004470; Expressed in pharyngeal gill and 13 other cell types or tissues.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14720; bZIP_NFE2-like; 1.
DR Gene3D; 1.10.880.10; Transcription factor, Skn-1-like, DNA-binding domain; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR004826; bZIP_Maf.
DR InterPro; IPR047167; NFE2-like.
DR InterPro; IPR008917; TF_DNA-bd_sf.
DR PANTHER; PTHR24411; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR; 1.
DR PANTHER; PTHR24411:SF3; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2; 1.
DR Pfam; PF03131; bZIP_Maf; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF47454; A DNA-binding domain in eukaryotic transcription factors; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 488..551
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 289..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 506..533
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 316..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 596 AA; 67516 MW; 3F7AB7C4A6C3AD00 CRC64;
SVMIEMEVMH SGHQDMELID ILWKQDIDLG ARREVFDYNH RQKEHELRRQ RELEEEKRQH
LVREREKALL AQLQLDEETG EYKDTQVQRV AVVTHVVRGT DPTSFDRNVN FPGETDDAMS
FDECLQLLAD TFPVEETETA SVCLDTAAVS APMMSPERPP LATPPERMSP DLEQAWMELL
SLPELQQCLS MQMEDTLETT TYPLSNSPEV QNPNYPFYPM NATDRLTNPL NVSPAQFMNT
FDGSLPSLVS PDSLHQVKEN SPQLNAKFNA EIFCDMFYPN DVLDESGGLE GNGSNAMPDI
SNKPPFTPVD LYSLSPDDAF DREKTNLTAE RPDSDSGISS NTSPNASSPG KSSHGDESFG
FSDSDMEEMD DNPGSVESDY SDMFSLNFQP DHLHQAISLS ARIGQPQQQQ EKNPKEHKTD
PDEESGHNSS PFAKDKQKKR SEKRLSRDEQ RAKALKIPFT VDMIINLPVD DFNEMMSKHQ
LNEAQLALVR DIRRRGKNKV AAQNCRKRKM ENIVGLESNL DSLKEEKERL LGEKSQNATS
LKEMKKQLNS LYLEVFSTLR DEKGSSYSPS DYSLQQSTDG SVFLVPRVKK TFLKSE
//
