ID G3NM57_GASAC Unreviewed; 355 AA.
AC G3NM57;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Nuclear transcription factor Y subunit gamma {ECO:0000256|ARBA:ARBA00040590};
DE AltName: Full=CAAT box DNA-binding protein subunit C {ECO:0000256|ARBA:ARBA00042333};
DE AltName: Full=Nuclear transcription factor Y subunit C {ECO:0000256|ARBA:ARBA00042663};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000006420.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000006420.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000006420.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes. NF-Y can function
CC as both an activator and a repressor, depending on its interacting
CC cofactors. {ECO:0000256|ARBA:ARBA00025263}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding.
CC {ECO:0000256|ARBA:ARBA00025911}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family.
CC {ECO:0000256|ARBA:ARBA00038129}.
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DR AlphaFoldDB; G3NM57; -.
DR STRING; 69293.ENSGACP00000006420; -.
DR Ensembl; ENSGACT00000006437.1; ENSGACP00000006420.1; ENSGACG00000004846.1.
DR eggNOG; KOG1657; Eukaryota.
DR GeneTree; ENSGT00940000155689; -.
DR InParanoid; G3NM57; -.
DR OMA; CVCCSHP; -.
DR TreeFam; TF354207; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000004846; Expressed in pharyngeal gill and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR PANTHER; PTHR10252; HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED; 1.
DR PANTHER; PTHR10252:SF8; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA; 1.
DR Pfam; PF00125; Histone; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 33..102
FT /note="Histone H2A/H2B/H3"
FT /evidence="ECO:0000259|Pfam:PF00125"
SQ SEQUENCE 355 AA; 39264 MW; 31F25525B11F1875 CRC64;
MSAEAFGAGG SDAQQTLQSF WPRVMEEIRN LTVDFRVQEL PLARIKKIMK LDEDVKMISA
EAPVLFAKAA QIFITELTLR AWIHTEDNKR RTLQRNDIAM AITKFDQFDF LIDIVPRDDL
KPPKRQEEMR QSVAPAEPVQ YYFTLAQQPG AVQVQGAQQA QQPGAQTATT IQPGQIIIAQ
PQQGQMLQGA TMQQLQHVQL QSQGTPITSA PVAMQVGEGQ QVQIVQASAA QGQAQTAQAQ
GQTMQVMQQI ITNTGEIQQI PVQLNTGQLQ YIRLSQPVSG AQVVQGQIQT LANAQQITQA
DVQQGQQQFN QFTDGQQLYQ IQQVTMPAGQ ELSQPMFIQS TNQTVDAQVT QVTTE
//
