ID G3NNK2_GASAC Unreviewed; 483 AA.
AC G3NNK2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Potassium voltage-gated channel subfamily A member 3 {ECO:0000313|Ensembl:ENSGACP00000006916.1};
GN Name=KCNA3 {ECO:0000313|Ensembl:ENSGACP00000006916.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000006916.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000006916.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000006916.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; G3NNK2; -.
DR STRING; 69293.ENSGACP00000006916; -.
DR Ensembl; ENSGACT00000006933.1; ENSGACP00000006916.1; ENSGACG00000005230.1.
DR eggNOG; KOG1545; Eukaryota.
DR GeneTree; ENSGT00940000160210; -.
DR InParanoid; G3NNK2; -.
DR OMA; GEEHQQY; -.
DR TreeFam; TF313103; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000005230; Expressed in diencephalon and 1 other cell type or tissue.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF28; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..133
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 54972 MW; 13DC7691B19258FB CRC64;
VMSAGNTPEE RAALSSSRPS LDRCERGRRG CCERVVINIS GLRFETQLKT FNQFPDTLLG
DPRKRMRYFD PLRNEYFFDR NRPSFDAILY YYQSGGRIRR PVNVPIDIFS EEIRFYQLGE
EAMEKFRDDE GFIKEEERVL PKREFQKQVW LLFEYPESSG PARGIAIVSV LVILISIVIF
CMETLPEFRD DRDQSTVAPA VNGTAPYVAS PFTDPFFVIE TLCIIWFSFE LLVRFFACPS
KARFSKNIMN IIDIVAIFPY FITLGTELAE KETNGGQQAM SLAILRVIRL VRVFRIFKLS
RHSKGLQILG QTLKASMREL GLLIFFLFIG VILFSSAVYF AEADDPSSSF TSIPDAFWWA
VVTMTTVGYG DMHPVTIGGK VVGSLCAIAG VLTIALPVPV IVSNFNYFYH RETDGEETPQ
YVHTSSCEHL PTEELRRSCS STSLSKSEYM VIEECIHSAF KQPNFSTENN QNCVNITKIF
TDV
//
