ID G3NR19_GASAC Unreviewed; 755 AA.
AC G3NR19;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl {ECO:0000313|Ensembl:ENSGACP00000007785.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000007785.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000007785.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000007785.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; G3NR19; -.
DR STRING; 69293.ENSGACP00000007785; -.
DR Ensembl; ENSGACT00000007804.1; ENSGACP00000007785.1; ENSGACG00000005862.1.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000157677; -.
DR InParanoid; G3NR19; -.
DR OMA; DLQAMYL; -.
DR TreeFam; TF352628; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000005862; Expressed in diencephalon and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0038191; F:neuropilin binding; IEA:Ensembl.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd05871; Ig_Sema3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF20; SEMAPHORIN-3G; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..483
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 532..630
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 722..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 85323 MW; A2C1CE468485E4B3 CRC64;
DLLSTNRSSI FSGHRDQLSL TAVFLDEYRD RLFLGGKDIL YSLMLGPVST ESKELHWPPL
PGNREDCIQT GKDPQTECAN FVRLLQPYNR THILACGTGA FQPMCAFVYV GHRGEEREHV
FTIDPTNVEN GRGKVPHDPS LPFASTFSGG ELYTGLTADF LGRDSVIFRS MGGRSTMRTE
TDHKLLHDPK FIAAHLVPDN DDRDNDKVYF FFTEKATEPG DREGAMHTRV GRVCANDVGG
QRVLVNKWST FIKARLVCSV PGPHGIDTHF NQLEDVFLLR TKDERNPDVY AIFSTISNVF
QGFAVCVYRM ADIREAFNGP FAHKEGPDYQ WGAYEGRVPY PRPGVCPSKI TNQPGREFGS
TKDFPDAVLQ FARSHPLMWR PVFPALRQPV LVKANIPYKL KQIVVDRVEA EDGQYDVMFI
GTDVGTVLKV IALHSGNSLD TEEVTLEELQ VFKVPTPITS MDISVKRQAL YVGSPAGVAQ
LKLHRCETYG KACAECCLAR DPYCAWDGSL CARYTPNSKR RYRRQDIKHG NPALQCVDQN
LSEDIDVTED RVVYGTENNS TFLECVPRSP QATVTWLIQR EDRREEVKLD ERVMSTEQGL
LFRRLSRQDE GTYVCRSREH GFTQTLARLS LEVLQGDTVD ELMARDGTGL SDSSFKDRSA
GGFRAWMPCS AFSRGGSPGQ IGQSRTWFKD IMQLIGSSNL PHVEEYCERM WCNDKLRRKH
KSMSEKYRQA QESARKARSR SSGERNRTPR DVSAW
//
