ID G3NTG4_GASAC Unreviewed; 817 AA.
AC G3NTG4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000008632.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000008632.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000008632.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3NTG4; -.
DR STRING; 69293.ENSGACP00000008632; -.
DR Ensembl; ENSGACT00000008651.1; ENSGACP00000008632.1; ENSGACG00000006529.1.
DR eggNOG; KOG1056; Eukaryota.
DR GeneTree; ENSGT00940000156136; -.
DR InParanoid; G3NTG4; -.
DR OMA; THCENTE; -.
DR TreeFam; TF331269; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000006529; Expressed in pharyngeal gill.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15287; 7tmC_TAS1R2a-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00592; CASENSINGR.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..817
FT /note="G-protein coupled receptors family 3 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003449015"
FT TRANSMEM 543..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 705..726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..759
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 765..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 544..802
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 817 AA; 92668 MW; 4D818A175427E723 CRC64;
RFFLSLLLLE SFLHESAQCT VQGSEFHLEG DYLLAGLFNI HHDSSPVVQD RPEAVNCSSK
PFLLSSYRRF QLMRFSVEEI NNSTDLLPNV SLGYEIFDHC SDIHSFPGIL KLLSVDGLIQ
PWAEPPKNLS KVMAVVGTYT STQALTVAPL FMMDLIPMVS YAASSSVFSR KQNFPSFLRT
VHPNKDVIEV IVNIMQHFNW SWVAFLHIDD DYGNDGRELF IKKIDGTEIC LGYTKGLDQH
TNYSQVFRQI EAHQITTIIV FAPEWTAEAL IKSAIQQNVT NKVWIAGDAW SLNKELPKEK
GIHNIGTILG VSEPKVTIPG FSDFIHHSKG QTHCENTEKS MFCNQVCNCS SLKPDEILNV
DPSYNFPVYA AVHAIAHALH NTLQCDSGRC NRSITAYPYM VLAELKKSNF TVLNQSVTFD
ENGDPNYGSY SIVFWNQSGD AQEIGFHNFY PNLYFFIDNS KIQWKTKEVP TSRCSQECDE
GSKKMPDGIH RCCFKCEICP KGTYFNKTED PYECINCKET EWSAAGSTSC NLRELEFVPF
TDIGAMLIMV GAWALVVLTV AMSVLFAINY NTPVVRSAGG PMCFLIFGCL CLSNVSVFFY
FGKPTASSCV MRLLPFLLFY TVCLACFVVR SFQIVFIFKI AAKFPKLHSV WIKYHGQWLF
ITLTFVTQAL FLLFGNMFAP AKPHNETSWY PDKTILICGM SNEAYVGPMV LLVSLCFLCF
IFSYMGKDLP KNYNEAKSIT FCLLLLILTW IIFATVFSLH RSKDIQTLNA VAILSSLYSF
LLWYFMPKCY IIIFQSHRNT QEYFQGLIQN YTTSLNQ
//
