ID G3NV63_GASAC Unreviewed; 984 AA.
AC G3NV63;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Si:dkey-178k16.1 {ECO:0000313|Ensembl:ENSGACP00000009232.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000009232.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000009232.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000009232.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3NV63; -.
DR STRING; 69293.ENSGACP00000009232; -.
DR Ensembl; ENSGACT00000009252.1; ENSGACP00000009232.1; ENSGACG00000006968.1.
DR eggNOG; KOG3527; Eukaryota.
DR GeneTree; ENSGT00940000155617; -.
DR InParanoid; G3NV63; -.
DR OMA; CEQQFLD; -.
DR TreeFam; TF351626; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000006968; Expressed in telencephalon and 1 other cell type or tissue.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF24; BAND 4.1-LIKE PROTEIN 1; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 2.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 23..303
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..830
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 984 AA; 110126 MW; BCADCBAC8C733431 CRC64;
SSEKTPSKAS KSPQKSSKRP KTVPVKVTLL DGSDYEAGVE KFAKGQTLLD MVCGHLNLLE
RDYFGLTFQD TDTAKHWLDP SKEIKKQILG SWIFGFSVKF YPPDPSVLIE DITRCTTCGL
QLRDDILGRL PCSFVTHALL GSYTVQAELG DYEAEDHGPD YVSDFRFAPN QTHELEERVM
ELHRNYRGMS PAEAEVNFLE NAKKLSMYGV DLHHAKDSEG IDIMLGVSAN GLLIYRDRLR
INRFAWPKIL KISYKRSNFY IKIRPGEYEQ FESTIGFKLP NHRASKRLWK VCIEHHTFFR
LVSPEPPPKG FLVIGSKFRY SGRTQAQTRQ ASALIDRPAP QFDRSVSKRY MLPRSIDGAS
ALGYSMEQLS HRSSSERTQF MSREDLDQEG SLDLDHDQYH YQDQDQEQDQ DQYPELDLEQ
HDGQNQDQVQ RQTWGSHIST TTKTLELKVQ GYTQNPASNT SSLPSALLLF LSCRVYAVVV
KHKKHFSRLF VTGGNSIVFV VITMIPTDYY PSVVNYDRNI KRELADAESA LLPFCRVNGF
PVKHANACLN LNCNLFSFNC LAARLFDSPA ALYLFVSARI CPPPSPSLPE PPFPTSCFAQ
TPFTPSRLPH LGFGHKDMAT HRPKQEMCPS LCKQQFLDKP DDVLQKHQAS INELKRALRQ
PNSKMAQREK RLSSATPPGG TPEREPEVPK IVPLKPQRSK KYLNNENSGV GSDQSRSDGG
VFGAAGDAQM TEPRDESCED TPPTPAIHEE PFNEASLKET HLGIERKCSS ITVSSTSSLE
AEVDFTVLTD LHSGMEEFSR GMTELGERDA SPDAEGVRPE VKRPDPVVPK KPKRSVPVSS
SVDREAGRVS AVTPLSREAS DVAPTPAARK TDVRTETQPN GSEVTTTIVE FTDQVHIGRE
ASRSPILITE NVTSATTHVS KTVKGGYSET RIEKRIIITG DDDVDQEQAL AIAIQEAKQQ
HPDMQVTKAV VVRETESSAE DRHS
//
