ID G3NXC6_GASAC Unreviewed; 603 AA.
AC G3NXC6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=FERM domain containing 3 {ECO:0000313|Ensembl:ENSGACP00000009995.1};
GN Name=FRMD3 {ECO:0000313|Ensembl:ENSGACP00000009995.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000009995.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000009995.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000009995.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3NXC6; -.
DR STRING; 69293.ENSGACP00000009995; -.
DR Ensembl; ENSGACT00000010017.1; ENSGACP00000009995.1; ENSGACG00000007535.1.
DR eggNOG; KOG3530; Eukaryota.
DR GeneTree; ENSGT00940000158577; -.
DR InParanoid; G3NXC6; -.
DR OMA; CPLRQWM; -.
DR TreeFam; TF343477; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000007535; Expressed in diencephalon and 2 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17102; FERM_F1_FRMD3; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF8; FERM DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 534..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..303
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 403..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 68647 MW; BDBE91BF01DE6913 CRC64;
RTDRRMKMLR FRSPSIRSLD QEVLCTIRLL DDTEISCSIQ RDTKGQFLLD HVCNHYNLLE
KDYFGIRYVD PERQRHWLEP NKPVVRQMKS HQPYTMCFRV KFYPHEPMKI REELTKYLLY
LQLKRDVYHG RLLCPFAEAA YLGACIIQAE LGDYDPEEHP SDYIRDFKLF PKQSLKLERK
IIEIHKNELR GQSAAFAELN MLQRAHSLET YGVDPHPCKD FTGSTAFLGF TATGFVVFQG
NKRIHLLKWA DVSKLKFEGK TFYVIGVQKE KKLVLTFHTS TPAACKHLWK CGVENQAFYK
CAKSSQIKTV SSSNIFFKGS RFRYSGRVAK EVIEASSKIQ REPPDVRRAQ FGQSRSFNSL
SHKNLIINME PLVPALPSTN EYEETAADAA GVVAVKDSVP LSPLKPAAPA DTQQQSSETP
KAEDDVVEDD EASGSLTISE LVYSPCASML PTPVDDSQGG VDLLFSSPVQ SPARMLRELH
ADPDIQAQLQ AERERDRARE RTRAAARGGM GGALASSLRL LSSNERFNAC VLSAARFVGV
VMGILLVTVP TLLLLLESDI DVSFLHEIRQ TPEFEQFHYE YYCPLRRWVL CRISMAMENL
WSD
//
