ID G3P0L6_GASAC Unreviewed; 1267 AA.
AC G3P0L6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=FLII actin remodeling protein {ECO:0000313|Ensembl:ENSGACP00000011139.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000011139.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000011139.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000011139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3P0L6; -.
DR STRING; 69293.ENSGACP00000011139; -.
DR Ensembl; ENSGACT00000011162.1; ENSGACP00000011139.1; ENSGACG00000008421.1.
DR eggNOG; KOG0444; Eukaryota.
DR GeneTree; ENSGT00940000156643; -.
DR InParanoid; G3P0L6; -.
DR OMA; CFHGWSA; -.
DR TreeFam; TF313468; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000008421; Expressed in intestinal epithelial cell and 13 other cell types or tissues.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd11280; gelsolin_like; 2.
DR CDD; cd11290; gelsolin_S1_like; 1.
DR CDD; cd11292; gelsolin_S3_like; 1.
DR CDD; cd11288; gelsolin_S5_like; 1.
DR CDD; cd11291; gelsolin_S6_like; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 3.40.20.10; Severin; 6.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007122; Villin/Gelsolin.
DR PANTHER; PTHR11977:SF139; PROTEIN FLIGHTLESS-1 HOMOLOG; 1.
DR PANTHER; PTHR11977; VILLIN; 1.
DR Pfam; PF00626; Gelsolin; 4.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 2.
DR PRINTS; PR00597; GELSOLIN.
DR SMART; SM00262; GEL; 6.
DR SMART; SM00364; LRR_BAC; 7.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 10.
DR SUPFAM; SSF55753; Actin depolymerizing proteins; 5.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 6.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 505..587
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 626..701
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 761..812
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 1176..1234
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 410..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 950..974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 855..909
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 950..969
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1267 AA; 144497 MW; 5CA0632807224790 CRC64;
MASTGVLPFI RGVDLSGNDF KGGYFPEHVK CMSSLRWLKL NRTGLCYLPE ELASLQKLEH
LSVSHNSLTT LHGELSSLPN LRAVVARANN LKNSGVPDDI FQLDDLSVLD LSYNQLTEIP
RDLENSRNML VLNLSHNNID SIPNQLFINL TDLLYLDLSD NKLDSLPPQM RRLVHLQTLT
LNNNPLMHAQ LRQLPAMVAL QTLHLRNTQR TQSNMPTSLE ALTHLADVDL SCNDLTRLPE
CLYSLSSLKR LNLSSNQISE LSLCIDQWTQ LETLNLSRNQ LTSLPSAICK LAKLKKLYIN
SNKLDFDGVP PGVGKLSSLT EFMAANNNLE LIPEGLCRCG KLKKLVLNKN RLVTLPEAIH
FLTDLEILDV RENPNLVMPP KPVDRAAEWY NIDFSLQNQL RLAGASPATV AAAGGGASPR
DPQARKMRLR RRKDSSQDDQ AKQVLKGMSD VAQGKNMEES EDSKYGDLKV RRWDKSLEKP
QLDYSEFYME DVGQVPGVTV WQIENFVPMQ VDDAFQGKFY EADCYIILKT FLDDNGALNW
DIYYWIGQEA TLDKKAGSAI HAVNLRNFLG AECRTIREEM GDESEEFSAV FNNEISYIEG
GTASGFYTVE DTNYSVRLYR VYGKKNIRLE SVPVKASSLD PRRYVFLSDT GLDIFIWRGA
NATLSSTTKA RLFAEKINKN ERKGKAEITT LLQSQEPPPF WEVLGGQPEE IKKHVPDDFT
PVRPKLYKVG LGLGYLELPQ INYKLSVEHK DHKIKLDTSP EMRLVQTLLD TKCVYILDCW
SDVFIWIGRK SPRLVRAAAL KLGQEICSML HRPKHACVTR NLEGTECQVF KSKFKNWDDV
LKVDYTRAAE TVHKNDNLQG KVKKDAEKKD QMKADLTALF LPRQPAMPLA EAEQLMEEWN
EDLDGMEGFV LEGKKFARLP EEEFGHFHTQ DCYVFLCRYW VPVEYDDEEK EKKEGSGGVE
GRRSTAEDDD DKQPEEDFQC VVYFWQGRQA SNMGWLTFTF SLQKKFESLF PGKLKVVRMT
QQQENLKFLS HFKRKFIIHK GKRKQKTDSA QPSLYHIRTN GSALCSRTIQ IGTDSCNLNS
EFCFILKVPF ESTDNQGIVY TWVGRAADPD EAKLAEDIMN CMFDETYSKQ VINEGEEPEN
FFWVGIGSQK PYDEDADYMK HARLFRCSNE KGYFSVSEKC SDFCQDDLAD DDIMLLDNGQ
EVYMWVGTQT SQVEIKLSLK ACQVYIQHMR AKDTEHPRKL RLVRKGNEPH CFNRCFHAWG
AFKTPPA
//
