ID G3P2K4_GASAC Unreviewed; 526 AA.
AC G3P2K4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Terminal nucleotidyltransferase 4A {ECO:0000313|Ensembl:ENSGACP00000011827.1};
GN Name=TENT4A {ECO:0000313|Ensembl:ENSGACP00000011827.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000011827.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000011827.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000011827.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3P2K4; -.
DR STRING; 69293.ENSGACP00000011827; -.
DR Ensembl; ENSGACT00000011851.1; ENSGACP00000011827.1; ENSGACG00000008953.1.
DR eggNOG; KOG1906; Eukaryota.
DR GeneTree; ENSGT00940000157811; -.
DR InParanoid; G3P2K4; -.
DR OMA; KWGSRVH; -.
DR TreeFam; TF313939; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000008953; Expressed in liver and 4 other cell types or tissues.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 16..110
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 177..236
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 307..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 58595 MW; BA991D3008B768B3 CRC64;
MSPRPEEAAM RKEVVNRIET IIKELWPTAD VQIFGSFSTG LYLPTSDIDL VVFGKWERPP
LQELEQALRK HNVAEPFSIK VLDKATVPII KLTEQETEGK VDISFNSETG VKAGLIKDYV
KMYPVLPYLI FVLKQFLLQR DLNEVFTGGI SSYSLILMVI SFLQLHPRID ARNPSENLGV
LLIEFFELYG RHFNYLKTGI RIKSGGAYIP KEEIMKAMTN GYRPSTLCIE DPLLPGNDVG
RGSYGALHVK QVFDYAYTVL SHAVSPLARS YPNKDSESTL GRIIRLTQEV IDYREWIIKK
WGGRDLTRSD NRVSSPKEPA SQPERCVEAE EQQRDSASPH SADSPMSISS PRQHSPASSV
SSLSGSDNDS DSALPCPVPR PPAMPPYPSF PHLGLALPPG LNLAPCKPGM GGHHLLLHPS
SQARVSLPGG LAMHSIPGRQ VCIDTVLPSF FHISFSCAVC QASSVKKLEV YLYMPQNAAN
FNVKGFHNPP LVNNPVLANR GHSHTQYHRN TWRRRKRDSL PVSLSR
//
