ID   G3P355_GASAC            Unreviewed;       621 AA.
AC   G3P355;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=NLR family, CARD domain containing 3 {ECO:0000313|Ensembl:ENSGACP00000012028.1};
GN   Name=NLRC3 {ECO:0000313|Ensembl:ENSGACP00000012028.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000012028.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000012028.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000012028.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3P355; -.
DR   Ensembl; ENSGACT00000012052.1; ENSGACP00000012028.1; ENSGACG00000009105.1.
DR   GeneTree; ENSGT00940000159861; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000009105; Expressed in spleen and 5 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF285; NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   DOMAIN          121..251
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   621 AA;  68669 MW;  A0478BC60F5D9391 CRC64;
     LLQRFSTASF LEVMLAHLRK VDAVSSAEET KIRGATRLHD QVNMVTTIVT AKGAQSSDAL
     RGFIESSDSQ VAQLVINHDI QQKEHDLMQV GATRGRKRNH LRQLGLTKLL EPLTRVSLPP
     RVSLTVGVAG IGKTTWVRHF VRQWSQGLIC ADVSFVLPFA VCELNSVEKV SAEKLVKLAF
     PHLTDPSVVL SSSCRTLLIL DGLDEFRCSA NFADAASCSD PKKEVSIDDL VTNIIRGNLL
     PDAAVWVTCR PRVASLIPGG LVDRVTEIPG FSPQDIRLFL DHHFSERDFG SKIWTHLESH
     KILMVMCYIP SVCWIVAETL VYIMRSETDE SLPRTCTELY AHFCSMKAEA GEPRGREPVK
     MEQLHGSNRK LLGNLGRLAF YGLLKHKYTF SEQDLRAYGI DLLLGQGSLG TGVLVREELA
     ICTTYRFTHL TLQEFLAATF YHISSKRAIF DLFSESTMSW PKIGFQNHFR SAFQHSQQAE
     DGHLDVFVRF LTGLLSPAAL KPLAGLLAVG KDEGNQKAFA AGFLQGLLVG GGAVVSLRAV
     NLAYCLHELQ HAELLRSVEE DLQLGSLAGK LTRAHCVVLG YLLHVSPECS EQTNLTGSLN
     YATVKCLLPQ LLYCSYLRSA P
//