ID G3P6Y7_GASAC Unreviewed; 449 AA.
AC G3P6Y7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000013361.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000013361.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000013361.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the formin homology family. Cappuccino
CC subfamily. {ECO:0000256|ARBA:ARBA00005271}.
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DR AlphaFoldDB; G3P6Y7; -.
DR STRING; 69293.ENSGACP00000013361; -.
DR Ensembl; ENSGACT00000013386.1; ENSGACP00000013361.1; ENSGACG00000010110.1.
DR eggNOG; KOG1922; Eukaryota.
DR GeneTree; ENSGT00940000154289; -.
DR InParanoid; G3P6Y7; -.
DR OMA; QKTSYNV; -.
DR TreeFam; TF326072; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000010110; Expressed in camera-type eye and 2 other cell types or tissues.
DR GO; GO:0005884; C:actin filament; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR001265; Formin_Cappuccino_subfam.
DR PANTHER; PTHR13037; FORMIN; 1.
DR PANTHER; PTHR13037:SF16; FORMIN-2; 1.
DR Pfam; PF02181; FH2; 1.
DR PRINTS; PR00828; FORMIN.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 8..416
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT COILED 290..317
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 449 AA; 51160 MW; EF503A8E2C8E3F27 CRC64;
MVQEAAPAKA AIEPPKPMKP LYWTRIQLIA KKPTSPLVWE TIEEPSVDFK EFVELFSKSA
VKEKKKPISD TISKSKAKQV VKLLNNKRSQ AVGILMSSIH LDMKDIQNAV LNMDNAVVDL
ETLQALYENR AQNDEMDGIK KHIKSSKDKE DAKPLDKPEQ FLFQLSQIPN FCERVFCILF
QSTFHECITS IVRKLEILER VCKTLQSGTC VSQVLGLVLA FGNFMNGGNR SRGQADGFTL
DILPKLKDVK SSDNSQSLLS YVVAYYLRHF DEDAGRETCV YSLPEPQDLF QASQMKFEDF
ERDLRKLRKD LNACSAQTEN VCKFSSEDIL QPFKGKMEEF LGQENDTLLC LKVLSFLELS
VSFSVKPKAG EKEVSPNTFF SIWHEFSTDF KDQWKKQNKL MLQERVKLAE ECFKQAKEKA
SYNVKPKHAT GIKESAWITC QTESALSRS
//
