ID   G3P9E8_GASAC            Unreviewed;       405 AA.
AC   G3P9E8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Nuclear envelope integral membrane protein 1 {ECO:0000313|Ensembl:ENSGACP00000014222.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000014222.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000014222.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000014222.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus inner membrane
CC       {ECO:0000256|ARBA:ARBA00004575}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004575}; Nucleoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004575}.
CC   -!- SIMILARITY: Belongs to the NEMP family.
CC       {ECO:0000256|ARBA:ARBA00005748}.
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DR   AlphaFoldDB; G3P9E8; -.
DR   STRING; 69293.ENSGACP00000014222; -.
DR   Ensembl; ENSGACT00000014247.1; ENSGACP00000014222.1; ENSGACG00000010747.1.
DR   eggNOG; KOG3817; Eukaryota.
DR   GeneTree; ENSGT00390000002174; -.
DR   InParanoid; G3P9E8; -.
DR   OMA; MAGCMKM; -.
DR   TreeFam; TF314831; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000010747; Expressed in embryo and 5 other cell types or tissues.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   InterPro; IPR019358; NEMP_fam.
DR   PANTHER; PTHR13598:SF4; NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1; 1.
DR   PANTHER; PTHR13598; UNCHARACTERIZED; 1.
DR   Pfam; PF10225; NEMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        124..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        180..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   405 AA;  46568 MW;  8DE413C0DA584814 CRC64;
     SVLSSNAGNQ LRVTDLRDGE EYVMSGSNRF CYKNSVFPNW RHTWTRIQVQ VWSSNVFKVE
     TVAGEEQLQD LDRFSIWGWF QSLLRERHNE TSINVNLFTK EMCFKVDPAD QTKYTVKPLR
     KFDIYLFLVF LAGASLFVFA GSLSRSQLFF YSAGMSTGMI ASLIILFFIL ARFLPKKSPF
     YVLIVGGWSF SVYAIQLVFR NLGVILQNHW NVVLGYVAVV GFITFAVCYR YGPLVDAKSI
     NILSWTLQLL GLLLIYLGIQ IQQVAFSIIV AAVFSKNLEY PVSLTVAACR KIKGYVRWKP
     EPRRLLSDEE YQKQGEEETL RALEELRKHC NSPEFSPWKA VSRLQSPKRF ADFIEGSPHL
     MSNEVSVHVQ EYGFGGSFFE DEFFDTDDDD EEQVNIKPMV IPELR
//