ID   G3P9P0_GASAC            Unreviewed;       794 AA.
AC   G3P9P0;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000014314.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000014314.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000014314.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; G3P9P0; -.
DR   STRING; 69293.ENSGACP00000014314; -.
DR   Ensembl; ENSGACT00000014339.1; ENSGACP00000014314.1; ENSGACG00000010807.1.
DR   eggNOG; KOG3611; Eukaryota.
DR   GeneTree; ENSGT00940000154870; -.
DR   InParanoid; G3P9P0; -.
DR   OMA; YINVQHF; -.
DR   TreeFam; TF352903; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000010807; Expressed in diencephalon and 2 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF14; SEMAPHORIN-4B; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        662..682
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..470
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   REGION          695..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..760
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   794 AA;  89091 MW;  22338D95801AADDE CRC64;
     ERTTRSFSLS GVFNFTSLLL SKEDNTLYVG AREILFALNL TDLSAIKLQR NLTWKTPERK
     RDECGFKGKN LQTDCFNYIK ILLRMNSTHL YVCGTYAFSP TCAYINTADF SLVKSDTGEI
     VTEDGRGRCP FNPEYKSTAI MADGELYAGT VSNFQGNEPI IYKGLRQGTS LKTENSLNWL
     QDPAFVGSAY IQESLPKGNL VGDDDKIYFF FSEAGKEFDF FDKTIVSRIA RVCKGDMGGE
     RVLQKKWTTF LKAQLLCTLP DDGFPFNIIQ DMFVLTPSPE DWKNTVFYGV FTSQWYNGAS
     GSSAVCSFTM DQVEKAFNGR YREVNRETQQ WYTYNHPVPE PRPGVCITNA AREDGISSSL
     HMPDKVLNFV KDHFLMDSVI RSQPLLLKRN VRYTQIAVHL VQAAKKAYNV IFIGTDDGRL
     HKAINVNNKM HIIEEMVIFR DSQPVQRIEL DTEKGQLYVS SFSELAAVPV ANCTNYQSCG
     ECILSRDPYC AWNGRLCVDV RRAAASSALQ QDIDEADTSA VCNKAVASPR LARPPPARMS
     SCQVIVIPAN TFQVLPCQLR SNLAERRWEF SESAGHFHYP SQQGGLVVVA QADRQETYEC
     WSVEEGFRQL LANFCVRGEA KQESTTLRGR SRPPQVSQGK ILTLPEEARS PQIDTKTYFN
     ELIVVCSLLA FSLLVFCLFA IFRNRGDVKS MLKEGERANM QQKKPRTVGK PAENLPLNGN
     AVPASASDHK GYQTLNDNYI CSTPPHEGPS PDNSRGFSEP ENKPPNLKES HVEVSPTCPR
     PRVRLGSEIK DSIV
//