ID   G3PA92_GASAC            Unreviewed;       472 AA.
AC   G3PA92;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Usher syndrome 1Ga (autosomal recessive) {ECO:0000313|Ensembl:ENSGACP00000014516.1};
GN   Name=USH1G {ECO:0000313|Ensembl:ENSGACP00000014516.1};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000014516.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000014516.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000014516.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; G3PA92; -.
DR   STRING; 69293.ENSGACP00000014516; -.
DR   Ensembl; ENSGACT00000014542.1; ENSGACP00000014516.1; ENSGACG00000010972.1.
DR   eggNOG; KOG0504; Eukaryota.
DR   GeneTree; ENSGT00390000017548; -.
DR   InParanoid; G3PA92; -.
DR   OMA; VMYVGTF; -.
DR   TreeFam; TF324946; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000010972; Expressed in intestinal epithelial cell and 2 other cell types or tissues.
DR   GO; GO:0050957; P:equilibrioception; IEA:InterPro.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IEA:InterPro.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:InterPro.
DR   CDD; cd21803; CEN_USH1G; 1.
DR   CDD; cd09586; SAM_USH1G; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR037602; USH1G_SAM.
DR   PANTHER; PTHR24161; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR24161:SF106; USHER SYNDROME TYPE-1G PROTEIN-LIKE; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          64..96
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          406..454
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|Pfam:PF00536"
SQ   SEQUENCE   472 AA;  53288 MW;  A3FC2458FEFF3AE2 CRC64;
     MNDRYHKAAR DGYLDLLKEA TRKDLNAPDE DGMSPTLWAA FHGNLEALRL IAARGGNPDK
     CDIWGNTPLH LAAANGHLNC LFFLVSFGAN IWCLDNDYHT PLDMAATKNH MDCVRYLDSI
     ATKQTGLNAK LVGKMKDRAF RDAERRIKDC VKMQKKHHKR MERRFHKETS EASASDAMSF
     SSYTSSSISH RLHNLNAATV SVPYSQATLH ATNRGKTKIQ RKLEKKKQGD GTFKIYEDGR
     KSVRSLSGLQ LGNDVMFVKQ GTYVNPKDRG RRNVREMFTR DNYDAISRAI SEPDLHGADV
     DYSEISTDSG HDSLFNRPGL GTMVFRRNYV SGGMFDIEGR DEDSADLSGN NVRLRSRLQQ
     YPSADEDSIG SARSLQVRNA EELPWEEVEL GLDDDDEADT SPLEVFLATQ SMTDFFSIFK
     REKIDLEALL LCSDHDLKSI HIPLGPRKKI LDACKRRMEA IEEPDCVEDT EL
//