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Database: UniProt
Entry: G3PCN3_GASAC
LinkDB: G3PCN3_GASAC
Original site: G3PCN3_GASAC 
ID   G3PCN3_GASAC            Unreviewed;       395 AA.
AC   G3PCN3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   16-OCT-2019, entry version 45.
DE   SubName: Full=Potassium inwardly-rectifying channel, subfamily J, member 14 {ECO:0000313|Ensembl:ENSGACP00000015357};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000015357, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000015357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000015357}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   STRING; 69293.ENSGACP00000015357; -.
DR   Ensembl; ENSGACT00000015387; ENSGACP00000015357; ENSGACG00000011616.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00960000186595; -.
DR   InParanoid; G3PCN3; -.
DR   OMA; QHGSQYE; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     87    113       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    161    185       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       52    190       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      197    370       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     49       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        176    176       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   395 AA;  44845 MW;  BEEB65399563B715 CRC64;
     GMCSGLRSVR GSSVGGRGKG RSSPDQDSLS SPSTIKRRRP RRSSRRPRQR FVGKDGRCNV
     TFVNMSERGQ RYLSDLFTTC VDIRWRWMLI IFTLSFLLSW LLFGFAFWLI AIVHGDLSIR
     LSPRPCFLQV NSFMAAFLFS LETQTSIGYG FRSVTEECPL AVMAVVLQCI VGCIIDAFII
     GAVMAKIAKP KKRNETLIFS DTAVVALRDG KLCMMWRVGN LRKSHLVEAH VRAQLLKPRV
     TEEGEFLPLD NMDINVGFDT GTDRIFLVSP VTIVHEINDE SPFFEIDRKT LEIDSELEVV
     VILEGMVEAT AMTTQCRSSY LASEILWGHR FEPVLFEKKD CYQVDYSFFH RTYEIPNTPS
     CSAKELAEQK YIQSSRSSFC YENEVALQLV SPDDE
//
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