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Database: UniProt
Entry: G3PDW6_GASAC
LinkDB: G3PDW6_GASAC
Original site: G3PDW6_GASAC 
ID   G3PDW6_GASAC            Unreviewed;      2747 AA.
AC   G3PDW6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   05-DEC-2018, entry version 44.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor, type 1b {ECO:0000313|Ensembl:ENSGACP00000015790};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000015790, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000015790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000015790}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   STRING; 69293.ENSGACP00000015790; -.
DR   Ensembl; ENSGACT00000015821; ENSGACP00000015790; ENSGACG00000011921.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   GeneTree; ENSGT00940000155071; -.
DR   OMA; PRHAPYK; -.
DR   TreeFam; TF312815; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007635};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2270   2292       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2304   2322       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2391   2416       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2436   2458       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2568   2591       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      112    166       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      173    223       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      231    287       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      294    358       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      379    435       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     1601   1621       {ECO:0000256|SAM:Coils}.
FT   COILED     2678   2726       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2747 AA;  312730 MW;  3E5EDBADF9EB18F6 CRC64;
     MSDKMSSFLH IGDVCSLYAE GSTNGFISTL GLVDDRCVVQ PDTGDLNNPP KKFRDCLFKL
     CPMNRYSAQK QFWKAAKPGG NSTTDTLLLT KLHHAADLEK KQNESENRKL LGSVIQYGNV
     IQLLHLKSNK YLTVNKRLPA LLEKNAMRVT LDSAGNEGSW FYIQPFYKLR SLGDSVVIGD
     KVVLNPVNAG QPLHASTHQL VDNPGCNEVN SVNCNTSWKV VLFMKWSDNK ETILKGGDVV
     RLFHAEQEKF LTCDDHRKQQ HVFLRTTGRQ SATSATSSKA LWEIEVVHHD PCRGGAGYWN
     SLFRFKHLAT GCYLAAEVSA DFEEESSEQR AALDADNEAL LGRLRAPQEK IMYSLVPVPD
     GMDISSIFEL DPTTLRGGDA MVPRSSYVRL RHLCTNTWVH STNNPIDKEE EKPVMLRIGT
     SAVKEDKEAF AIVPVPPAEV RDLDFANDAS KVLASIAGKL ERGTITQNER RFVTKLLEDL
     VFFVVDIPNS GQDVLEIMVN KPNRERQKLM REQNILKQIF KLLQAPFTDS GDGPMLRLEE
     LGDQRHAPFR HICRLCYRVL RHSQQDYRKN QEYIAKQFRF MQKQIGYDVL AEDTITALLH
     NNRKLLEKHI TAAEIDTFVT LVRKNREPRF LDYLSDLCVS MQKSIPVTQE LICNSVLDPI
     NGDILIETKL VLSRFEIETI TNEEGPVEPE DEEEVWLFWK DNCKEIRSKS VRELAQDAKE
     GQKEDQEVVS YYRCQLNLFA RMCLDRQYLA INKISGQLDV DLILRCMSDE DLPFDLRASF
     CRLMLHMHVD RDPQEQVTPV KYARLWSEIP SKIAIDDYDN DGTTRDEIKE RFCLTMDFVE
     NYLREVVSQN VPFTDREKNK LTFEVVNLAR NLIYFGFYNF SDLLRLTKIL LNILDCVHVN
     TIYPVTKIEK GEDNKGKHSV RLRFDRNVMK SIHGVGELMT QVVLRGGGLL PTVPAHQPEG
     DVAKAQVEPE REDIMVMDTK LKVIEILQFI LNVRLDYRIS CLLCIFKREF DENNPQADSS
     QNGTNNAPGQ MPGNLDFENI EEQAEGIFGG SEENTPLDLD DHGGRTFLRV LLHLTMHDYP
     PLVSGALHLL FRHFSQRQEV LMAFKQVQLL VTSQDVDNYK QIKSDLDQLR SIVEKSELWV
     YKRQGEDGMD GEGPSESENK NKGDSPGSDK KKSESTSSYN YRVVKEVLLR LSRLCVQEGS
     SGKKSRKQQQ RLLRNMGAHS VVLELLQIPY EKGEDVRMQE IMKQAHEFLQ NFCAGNQQNQ
     ILLHKHINLF LNPGILEAVT MQHIFMNNFQ LCSEINERVV QHFVHCTETH GRHVQYLKFL
     QTIVKAESKF IKKCQDIVMA ELVNSGEDIL VFYNDRASFQ TLVQMMRSER DRMDENSPLM
     YHIHLVELLA VCTEGKNVYT EIKCNSLLPL DDIVRVVTHE DCIPEVKIAY INFLNHCYVD
     TEVEMKEIYT SNHMWKLFEN FLVDICRVCN NTSDRKHADT ILERYVTETV MSIVTCFFSS
     PFSDQSTSLQ TRQPVFVQLL QGVFRVYHCN WLNPVQKASV EACIKVLSDV AKSRAIAIPV
     DLDSQVNNLF VKSNNVVQKS ILSWRLSAKN TTRRDSGQTS SKDYRNIIER LQDIVSALED
     RLRPLVQAEL SVLVDVLHRP ELLFPENTEA RKKCESGGFI SKLIKHTKQL LEENEERLCI
     KVLQTLREMM TKDRGYGEKL IAFDDEMDVA ELAPPPEPQV PAEELDPTQP QKQLDDQRRG
     EALRQILVNR YYGNVKAGQR RESLTAFNNG PLAAGAPGKS PTVVSSGVGG RGELSLAEVQ
     CHLDKEGASD LVIDLIMNAT SDRIFQESIL LAIALLEGGN TVIQRSFFER LTGDNKSEKF
     FKVFYERMKL AQQEIKATVS VNTSDLGSKK KDEEPPDKDA PARKKVKDVL LVAVVTEEVK
     EQLAEASAVT KKAFTTYRRE AEAEEHQTAA DGTPVPTPDK SQEEGEMSVI ITIMQPILRL
     MQLLCENHNR ELQNFLRNQN NKNNYNLVCE TLQFLDCICG STTGGLGLLG LYINEKNVGL
     INQTVESLTE YCQGPCHENQ NCIATHECNG IDIIIALILN DINPLGKKRM DLVLELKNNA
     SKLLLAIMES RHDSENAERI LYNMRPKELV EVIKKAYMHS ASPRNVGHNI YILAHQLARH
     NKELQAMLKP GGTYGEGDEA LEFYAKHTAQ IEIVRLDRTM EQIVFPVPNI CEFLTQESKL
     RVYYTTERDE QGSKINDFFL RSEDLFNEMN WQKKLRAQPI LYWCSRNMTF WSSISFNLAV
     LMNLLVAFFY PLEGVRGGTL EPHLSALLWM ALLVSLAIVI VLPQPHGIRA LIASAILRLI
     FSVGLEPTLL LLGGCNLCNK VIFLTSFVGN RGTFTRGYIA MIMDVEFLYH LLYLIICSLG
     VFVHVFFYSL LLFDLVYREE TLLNVIKSVT RNGRSIVLTA VLALILVYLF SIVGYIFFKD
     DFILAVDRIP NKTLGAEHGA SMVGEYFSGV CQKDGGENCS TEAVMDASVV VQPSAVVIED
     KERSCDSLLM CIVTVLSHGL RSGGGVGDVL RKPSKEEPLF AARVIYDMLF FFMVIIIVLN
     LIFGVIIDTF ADLRSEKQKK EEVLKTTCFI CGLERDKFDN KTVTFEEHIK VEHNMWHYLC
     FIVLVKVKDS TEYTGPESYV AQMIREHNLD WFPRMRAMSL VSSDADGEQN EIRNLQEKLE
     STMKLVSNLS GQLTELKEQM TEQRKQKQRI GLLAHPQHMN VNPQQPA
//
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