ID   G3PKV1_GASAC            Unreviewed;       454 AA.
AC   G3PKV1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Translation initiation factor eIF2B subunit gamma {ECO:0000256|ARBA:ARBA00044196};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit gamma {ECO:0000256|ARBA:ARBA00044229};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000018231.1, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000018231.1, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000018231.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC       {ECO:0000256|ARBA:ARBA00007878}.
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DR   AlphaFoldDB; G3PKV1; -.
DR   Ensembl; ENSGACT00000018266.1; ENSGACP00000018231.1; ENSGACG00000013800.1.
DR   GeneTree; ENSGT00510000047486; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000013800; Expressed in muscle tissue and 14 other cell types or tissues.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd04198; eIF-2B_gamma_N; 1.
DR   CDD; cd04652; LbH_eIF2B_gamma_C; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR45989; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR   PANTHER; PTHR45989:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   DOMAIN          5..138
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   REGION          244..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..258
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   454 AA;  50199 MW;  79355373FB4A0725 CRC64;
     MELQAVLMAA GGGSRMPDLT YNTPKPMLPV GNKPLMWHPL NLLERVGFEE VIVITTKEVQ
     KMMSTDPKMK DVKMKLDVVC IQEDGDMGTA DALRHIQQKI KTDVLVVSCD LITDVALHEV
     VDLFRAHNAT LAMLMSKAHD FTETVPGQKG KKKTGEQRDF VGVDQSGKRL LFMANEADLE
     DGLSIRKSIM RKHPRMHIKT GLVDAHLYCL KKAVVDFLAD NKSISSIRGE LLPYLVRKQF
     SKTTNCPKSK DDADDQTQKT ADGSTNSTEL LICSRDEPLL QLAQERSCWN DHRGDMSEAY
     HGGKLRCYVH IMDQGLCYRV NTLAAYIEAN RLVSRTFVKH AVFVMTPLLG GQMGPDSIIG
     AQCQVADKTS IKRSTIGNST TVKEKVKVTN SIIMHGVTIE EGCNIHGCVI CSNAVIGRGA
     DLKYCLVGNG QQIEAEGEAH SFHTSTFNML SLFS
//