ID G3PPK4_GASAC Unreviewed; 400 AA.
AC G3PPK4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Voltage-dependent L-type calcium channel subunit beta-3 {ECO:0000256|ARBA:ARBA00019004};
DE AltName: Full=Calcium channel voltage-dependent subunit beta 3 {ECO:0000256|ARBA:ARBA00030522};
GN Name=CACNB4 {ECO:0000313|Ensembl:ENSGACP00000019538.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000019538.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000019538.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000019538.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
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DR AlphaFoldDB; G3PPK4; -.
DR Ensembl; ENSGACT00000019576.1; ENSGACP00000019538.1; ENSGACG00000014790.1.
DR GeneTree; ENSGT00950000182837; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000014790; Expressed in diencephalon and 4 other cell types or tissues.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd12043; SH3_CACNB4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR008079; VDCC_L_b3su.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824:SF15; CALCIUM CHANNEL, VOLTAGE-DEPENDENT, BETA 4B SUBUNIT; 1.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR PRINTS; PR01696; LCACHANNELB3.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 58..127
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 14..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 44426 MW; 112B1F15E8FB8CFE CRC64;
MYDNLYLHGF EDSEAGSADS YTSRPSDSDV SLEEEREVQA QEREQQAATQ LERAKTKPVA
FAVRTNVSYC GALDEDVPVP ATAISFDAKD FLHIKEKFNN DWWIGRLVKE GCEIGFIPSP
LKLENIRLQQ EQKRGRVQGK SGGNSSSSVE DEVSASIRPL ISSAGKQKQK VTEHVPPYDV
VPSMRPVVLV GPSLKGYEVT DMMQKALFDF LKHRFDGRIS ITRVTADISL AKRSVLNNPS
KRAIIERSNT RSSLAEVQSE IERIFELARS LQLVVLDADT INHPAQLLKT SLAPIIVHVK
VSSPKVLQRL VKSRGKSQSK HLNVQLVAAD KLAQCPPEMF DIILDENQLE DACEHLAEYL
EAYWKATHTS LATPLNPLLG RNLGPTTLTP YPTSISGLQV
//
