ID G3PQZ3_GASAC Unreviewed; 1715 AA.
AC G3PQZ3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Lymphocyte antigen 75 {ECO:0000313|Ensembl:ENSGACP00000020028.1};
GN Name=LY75 {ECO:0000313|Ensembl:ENSGACP00000020028.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000020028.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000020028.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000020028.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 69293.ENSGACP00000020028; -.
DR Ensembl; ENSGACT00000020067.1; ENSGACP00000020028.1; ENSGACG00000015184.1.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT01050000244842; -.
DR InParanoid; G3PQZ3; -.
DR OMA; MITKNRH; -.
DR TreeFam; TF316663; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000015184; Expressed in testis and 12 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 9.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 10.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF65; LYMPHOCYTE ANTIGEN 75; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 9.
DR SMART; SM00034; CLECT; 10.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 10.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 9.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00479}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1665..1686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..182
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 195..312
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 340..461
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 481..586
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 624..766
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 929..1054
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1092..1194
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1231..1339
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1378..1487
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1529..1654
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DISULFID 139..165
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 153..180
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
SQ SEQUENCE 1715 AA; 192116 MW; 878C9EDB83361966 CRC64;
TDKDAFTIQH SSTRTCLTTG ASSTPSLAPC DPDGRSQLWK WGSNHRLFHV DTSLCLALDV
RSKELSLVDC GSNVLLWWRC LDGAVYTVYQ MGLGVSEGKV SAKRDSNDTW VRGASRDDIC
QQPYRVVHTS GGNSAGSPCE FPFKHNGSWH HGCLPDPDLT GLSWCATTPD YDRDRKNGVC
LTPEEGCKTL FAGPEGDSCY EFVSGVAVTW EEALDSCRSQ GADLLSVSRP EDLHSKTLLD
GLDGMPERMW IGLHQLDASH GWQWSDGSPL TTLRWETGMP STGLLASDCG VLNSKQSYES
EQCSQKLPYV CKKSFNASHV AAAETLLYDS TVCAGDWVPW NGWCYKLVNQ AKNFTDARIH
CSQPEEGVLG SLASLHSVDT MEMISTHFHS DGNALNVWIG LMGVGVNPAV FKWIDHAPVT
FTYWDQNQPV QPAVDPSCVF YSGHHGWRVG DCTLRRPFMC QTKGEANKSA TQTGCRFEDG
WRRHGNSCYQ VNPNQVFFKD RCNITVNNRF EQAFISRLLR EQIEAEPQYF WLGLQDVNNT
GEYQFVSRNG TPGVVPYTNW GVFHPHLDGS CAVISKLSGK WDVRNCTTFK AGTICRTDLG
PPPPPEPEPN PNATCPDGWV SKVNSMYCYK AFHQERLSRK RSWEEAERFC LALGANLPSF
TSNYEMRVLH SILRDSISDN RYFWVGLNRR NPADRSWQWS NGQPVSMDIL QQDFHEDDAY
DRHCTAFKTS KSTLKHLFVF LLHDLPPTPF YATPFHCDAR LEWVCQLPRG KTPKTPEWYN
PGGHHESSIF VDGAEFWFVE EPKLSFEEAT LFCSMNGSRL AAPITSTAVG KIQQHLKEMS
GSSSQSWWID LREPGRIFPM TYNQMYFYHS ILLGRCTTIS PEDSFPDHDQ SCRLPLSFVC
ERHNVTSVEI NPLEPRPAGK SCGNESLSFR NKCYTLMRSQ KPVSFAYASG VCQSVRGTLV
TISDQAEQDF LTTLLPKMRN MDRIWIGLKL KYGNPEWVDQ SPVDYVNINP LVLGMHRDIK
VNTWDVDSMD LCVFLINNPN SAMLGTWDYS SCTQFQNLAF CQHYAGKALK TRGLLVPDKP
VEPHVPKESF TVNNHTILLL DRNLTWFEAL EQCRKNNMDL ASVADTFLQA TLTVYVSNAR
KPMWIGLFSE DDGIHYRWTD HSHTVFSRWS SDVTGGSCVY LDIDGFWKAT ECEEVLGGAI
CHKPHEEIIT TPEDVAVKCP HKINGPNWIP FKNNCYSFKL VSTRWEPFDQ GQILDTCKTL
HANADILTIR NAEENEFVKQ QLLPFQNLVQ FVWLGLFKDD NDNQIKWYDG TNVQYSNWAN
GRPDVDGAFM AGLTASGTWM LVSNRKLFAQ FKQMSIVTCK LDNGGQRYNL SSADFQHYGN
LSYKVVTRKL SWHQALEACG QGGGHLASIH DIQHSAHVKL IAQTDGFPLW IGLSHHDVSD
SAFEWSDGTT FNYKASITDS RESPASNEAS CVHVSPAGDW LKASCNKLLD GAICYTTAIT
TASQRAKTQA PPEAKGCPGS SGVSKWVQHE GHCYAFDMSF YNFHVHSMEQ AKSLCQSMDA
KLLSLKTKEE NDFVSKYMFD DPLITSRVWL AMDVNAEGKP LSWQDGSALS FSNWAPGALV
AGKKPTPRCA VMVAGDDGVW KLVSCNDSYS RVVCTTEAKS GGSPVALGLF VVVFLAFLGA
VAFILYKKRG GRFSSAVRYK RTYDDADGAS IIEAD
//
