ID G3PRA6_GASAC Unreviewed; 1141 AA.
AC G3PRA6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Protocadherin 17 {ECO:0000313|Ensembl:ENSGACP00000020141.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000020141.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000020141.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000020141.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3PRA6; -.
DR STRING; 69293.ENSGACP00000020141; -.
DR Ensembl; ENSGACT00000020180.1; ENSGACP00000020141.1; ENSGACG00000015275.1.
DR eggNOG; KOG3594; Eukaryota.
DR GeneTree; ENSGT00940000156894; -.
DR InParanoid; G3PRA6; -.
DR OMA; CYVPDRI; -.
DR TreeFam; TF352008; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000015275; Expressed in telencephalon and 4 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR GO; GO:0060219; P:camera-type eye photoreceptor cell differentiation; IEA:Ensembl.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF41; PROTOCADHERIN-17; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1141
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003449955"
FT TRANSMEM 683..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..128
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 129..239
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 240..347
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 349..453
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 454..563
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 569..675
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 834..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1030
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1141 AA; 125674 MW; 7A28C782894785E7 CRC64;
MYLSVFFFLL LWAQALTLKN LNYSVPEEQG PGTVIGNIAK DARLGLEQVG PGGQGKKANF
RVLENSAPHL IDVDPQSGLL YTKQRIDRET LCKRNPKCQL SMEVFANDKE ICMIKIDIQD
INDNSPNFPS DQIDIDISEN AVPGTRFPLT SAHDPDAGEN GLKTYQITRD DYNLFSLEVK
SRGDGTKFPE LVIQRPLDRE VRNHHTLILS ATDGGEYPRS GTMQINVKVI DSNDNSPVFD
QPSYVVEIPE NSPPGKLLID LNATDPDEGN NGQVVYSFSG YAPERIRELF SIDSRTGVIK
IQGEIDYEES PVIEIDVQAK DLGPNPIPGH CKVTVKVLDR NDNWPSIGFV SVRQGAISEA
APPGTVIALV RVTDKDSGRN GQLQCRVLGN VPFKLEENYD NFYTVVTDRP LDREAQDEYN
VTIVAKDNGI PPLNSTKSFT VKILDENDNV PRFTKSVYLL QIPENNIPGE YLGSVLAHDP
DLGQNGTVYY SIIYSNVSGG DVNTYVNVNA ANGAIYAVRS FNYEQIKYFD FKVLARDSGS
PQLESNATVR ISVLDVNDNI PVIVLPLLLN DTAEIHVPRN VGVGYIVTTV RAVDNDYGES
GRLTYEISDG NEEHLFEIDP VTGEVRTAHP FWDDVNPLAE LIIRVSDHGK PTLTAAARLF
IKASNGRPPD GLPRTKENLN WDMSLPLIVT LSIISIMLLA AMVTIAIKCK RENKEIRTYN
CRIAEYSHPQ LGKGKKKKIN KNDIMLVQSE VEERDAMNVM NVVSSPSLAT SPMYFDYQTR
LPLSSPRSEV MYLKPTANNL SVPQGHVGCH TSFTGPVTST TDTPTNRMSI IQTDNFPTEP
NYMGSRQQFV QSSSTFKDPE RASLRDSGHG DSDQADSDQD TNKGSCCDMS AKEALKLKAT
GVKPPPLEQA DEDCVNCTEE CRVLGHSDRC WMPQFPAGGN QAEGVDYRNN MFVPAGMETP
EAETYETVNP NGKKTFCTFE KRATVTPPSL VANVKPYLKA KRALSPLLQE VPSASGSPTK
GCSTMPPCSS VKSPADGAEG KPPPATCSGH YGPPDGQYLS PNKQTRDQGV YQPLPHSDPV
AKVLAEARSR ISQEATREME CVLEQVEPDA NRDRMDGDQV VRDIDKLLQD CRGSEASGTL
R
//
